Diversity of the midstream urine microbiome in adults with chronic kidney disease

AbstractPurposeTo examine the characteristics of the midstream urine microbiome in adults with stage 3 –5 non-dialysis-dependent chronic kidney disease (CKD).MethodsPatients with non-dialysis-dependent CKD (estimated glomerular filtration rate [eGFR]    50% reads) by the generaCorynebacterium (n = 11),Staphylococcus (n = 9),Streptococcus (n = 7),Lactobacillus (n = 7),Gardnerella (n = 7),Prevotella (n = 4),Escherichia_Shigella (n = 3), andEnterobacteriaceae (n = 2); the rest lacked a dominant genus. The samples had high levels of diversity, as measured by the inverse Simpson [7.24 (95% CI 6.76, 7.81)], Chao [558.24 (95% CI 381.70, 879.35)], and Shannon indices [2.60 (95% CI 2.51, 2.69)]. Diversity measures were generally higher in participants with u rgency urinary incontinence and higher estimated glomerular filtration rate (eGFR). After controlling for demographics and diabetes status, microbiome diversity was significantly associated with estimated eGFR (P 
Source: International Urology and Nephrology - Category: Urology & Nephrology Source Type: research

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Source: Redox Biology - Category: Biology Source Type: research
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Source: Journal of Physiology and Pharmacology - Category: Drugs & Pharmacology Tags: J Physiol Pharmacol Source Type: research
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Source: European Cytokine Network - Category: Molecular Biology Tags: Eur Cytokine Netw Source Type: research
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Source: European Cytokine Network - Category: Molecular Biology Tags: Eur Cytokine Netw Source Type: research
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Source: The Egyptian Journal of Critical Care Medicine - Category: Intensive Care Source Type: research
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Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research
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Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research
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Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research
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Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research
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Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research
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