Longitudinal associations of lifetime adiposity with leukocyte telomere length and mitochondrial DNA copy number

In conclusion, telomere attrition may be accelerated by marked weight gain in middle life, whereas mtCN is likely to be reduced persistently by adiposity over the life course. The findings indicate the importance of lifetime weight management to preserve functional telomeres and mitoch ondria.
Source: European Journal of Epidemiology - Category: Epidemiology Source Type: research