Lesion-Specific and Vessel-Related Determinants of Fractional Flow Reserve Beyond Coronary Artery Stenosis

Conclusions
In addition to the severity of luminal stenosis, necrotic core volume is an independent predictor of FFR. The distribution of plaque characteristics among lesions with varying luminal stenosis and normal and abnormal FFR may explain the outcomes associated with FFR-guided therapy.

Source: Journal of the American College of Cardiology: Cardiovascular Imaging - April 2, 2018 Category: Radiology Authors: Ahmadi, A., Leipsic, J., Ovrehus, K. A., Gaur, S., Bagiella, E., Ko, B., Dey, D., LaRocca, G., Jensen, J. M., Botker, H. E., Achenbach, S., De Bruyne, B., Norgaard, B. L., Narula, J. Tags: Original Research Source Type: research