TET-2 up-regulation is associated with the anti-inflammatory action of Vicenin-2.

This study demonstrates that the anti-inflammatory actions of V-2 are associated not only with increased IL-10 and IL-1Ra expression, but also with TET-2 up-regulation. Further work is required to establish if the effects of V-2 can be definitively linked to TET-2 activity and that these actions are mirrored in a range of relevant cell types.
PMID: 29567563 [PubMed - as supplied by publisher]

Source: Cytokine - March 19, 2018 Category: Molecular Biology Authors: Hassan N, Ali A, Withycombe C, Ahluwalia M, Al-Nasseri RH, Tonks A, Morris K Tags: Cytokine Source Type: research