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BD Scores a Victory in Bard 's Hernia Mesh Case

Becton Dickinson, which acquired C.R. Bard at the end of 2017, scored a victory in New Jersey Superior Court this week. The court's appellate division refused to reinstate a product liability lawsuit involving Bard's 3DMax polypropylene mesh, which is used for hernia repair.  Plaintiff Kemuel Goodson was implanted with the product in 2006 and alleged that the mesh caused multiple complications that required extensive medical care, including several additional operations. Goodson claimed in his original complaint that defective design, negligence, and fraud and misrepresentation were to blame for the complications he suffered after receiving the mesh implant. The three-judge appellate panel noted in their decision that the company has continued to be in compliance with FDA requirements, and has never had to recall the 3DMax product from the market. Mark Middleton, MD, who performed Goodson's surgery in Hiram, Georgia, testified that he was aware of the risks and benefits of using synthetic mesh, including the risks of chronic pain, infertility, and nerve ingrowth. Middleton also said he discussed the risks of numbness and chronic pain with Goodson before the surgery, but did not read the instructions for use. He testified that he had experienced fewer problems with the 3DMax mesh than any other mesh products he has used and that he does not believe the device caused Goodson's complications. “In the instant case, none of the experts specifica...
Source: MDDI - Category: Medical Devices Authors: Tags: Business Design Source Type: news

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Conclusion: Given that the majority of surveyed physicians support MMJ as an option for patients, few are registered and have adequate knowledge of MMJ. Although our study sample is small and geographically limited, our survey results highlight key physician issues that are likely applicable to practitioners in other states. Concerted efforts are needed at the federal, state, and academic levels to provide practitioners with evidence-based guidelines for the safe use of MMJ. PMID: 29662957 [PubMed]
Source: Pain Physician - Category: Anesthesiology Authors: Tags: Cannabis Cannabinoid Res Source Type: research
FATAL HONEY POISONING IN SOUTHWEST CHINA: A CASE SERIES OF 31 CASES. Southeast Asian J Trop Med Public Health. 2017 Jan;48(1):189-96 Authors: Zhang Q, Chen X, Chen S, Ye Y, Luo J, Li J, Yu S, Liu H, Liu Z Abstract Honey poisoning cases occur in southwestern China. In this case series, we attempted to determine the symptoms and causes of honey poisoning from 2007 to 2012 in southwestern China. We also conducted a quantitative melissopalynological analysis of honey samples. During the study period, 31 honey poisoning cases occurred in the study location, all during July to August. All the cases occurred ...
Source: Southeast Asian Journal of Tropical Medicine and Public Health - Category: Tropical Medicine Tags: Southeast Asian J Trop Med Public Health Source Type: research
We present 2 cases of scrub typhus with cholecystitis. The first patient is a 62 year old female who presented to the hospital with fever and body aches for 1 week and right upper quadrant abdominal pain for 3 days. She gave a history of an insect bite 2 weeks previously. She was diagnosed as having acute cholecystitis and underwent cholecystectomy. She continued with fever post-operatively and physical examination revealed an eschar. She had an immunofluorescence assay (IFA) performed that revealed a high IgM titer for Orientia tsutsugamushi. She was diagnosed as having scrub typhus, treated with doxycycline and she recov...
Source: Southeast Asian Journal of Tropical Medicine and Public Health - Category: Tropical Medicine Tags: Southeast Asian J Trop Med Public Health Source Type: research
CONCLUSIONS: A novel instrument based on an operationalization of the IASP criteria can not only discern between LNP and nLNP, but also provide a high level of diagnostic certainty about the presence of NP after a short clinical encounter. PMID: 29661030 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research
We report a case of CSOA with a persistent LSVC that was managed through coronary sinus rerouting during a total cavopulmonary connection, and provide a review of the literature regarding this rare anomaly. PMID: 29662811 [PubMed]
Source: Korean Journal of Thoracic and Cardiovascular Surgery - Category: Cardiovascular & Thoracic Surgery Tags: Korean J Thorac Cardiovasc Surg Source Type: research
Authors: Jung W, Choi JW, Hwang HY, Kim KH Abstract Background: We evaluated the early clinical outcomes of tricuspid valve annuloplasty (TAP) with the Tri-Ad annuloplasty ring for functional tricuspid regurgitation (TR). Methods: From January 2015 to March 2017, 36 patients underwent TAP with a Tri-Ad ring for functional TR. To evaluate the early clinical outcomes of TAP with the Tri-Ad ring, we conducted a propensity score-matched analysis comparing the Tri-Ad and MC3 tricuspid annuloplasty rings (n=34 in each group). The follow-up duration was 11.0±7.07 months. Results: There was 1 case of operati...
Source: Korean Journal of Thoracic and Cardiovascular Surgery - Category: Cardiovascular & Thoracic Surgery Tags: Korean J Thorac Cardiovasc Surg Source Type: research
Autophagy inhibition potentiates SAHA‑mediated apoptosis in glioblastoma cells by accumulation of damaged mitochondria. Oncol Rep. 2018 Apr 16;: Authors: Lohitesh K, Saini H, Srivastava A, Mukherjee S, Roy A, Chowdhury R Abstract Glioblastoma multiforme (GBM), often referred to as a grade IV astrocytoma, is the most invasive type of tumor arising from glial cells. The main treatment options for GBM include surgery, radiation and chemotherapy. However, these treatments tend to be only palliative rather than curative. Poor prognosis of GBM is due to its marked resistance to standard therapy. Curre...
Source: Oncology Reports - Category: Cancer & Oncology Tags: Oncol Rep Source Type: research
BACK pain is common and usually clears up quickly, within a few weeks, as long as it is not linked to a more serious health problem. The symptoms can be debilitating, but while you wait for your back to improve, sleeping in a particular position can help.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
IPSC‑MSC inhibition assessment in Raw 264.7 cells following oxygen and glucose deprivation reveals a distinct function for cardiopulmonary resuscitation. Mol Med Rep. 2018 Apr 11;: Authors: Yu Y, Wang D, Li H, Liu Y, Xiang Z, Wu J, Jing X Abstract Hypoxia is a serious stress state. The nervous system is less tolerant to hypoxia, and cell death due to hypoxia is irreversible. With the incidence of cardiovascular disease gradually increasing, the sudden cardiac death rate is additionally increasing. Although cardiopulmonary resuscitation (CPR) is an important development, recovery is frequently poor. I...
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
Authors: Song D, Qi W, Lv M, Yuan C, Tian K, Zhang F Abstract Osteoarthritis (OA) is a common type of arthritis, which may cause pain and disability. Alterations in gene expression and DNA methylation have been proven to be associated with the development of OA. The aim of the present study was to identify potential therapeutic targets and associated processes for OA via the combined analysis of gene expression and DNA methylation datasets. The gene expression and DNA methylation profiles were obtained from the Gene Expression Omnibus, and differentially expressed genes (DEGs) and differentially methylated sites (D...
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
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