Combined BRAF V600E analysis and 99m Tc-MIBI scintigraphy can be a useful diagnostic tool in differentiated thyroid cancer patients with incomplete bio-chemical response to first radioiodine therapy (RAIT): a pilot investigation

ConclusionAlbeit obtained in a small retrospective series, our results suggest that the combination of BRAFV600E+ve mutation and MIBI −ve scintigraphy may be considered a negative prognostic clue, which predicts the absence of radioiodine uptake at pT-WBS in DTC patients with incomplete bio-chemical response to first RAIT.
Source: Journal of Endocrinological Investigation - Category: Endocrinology Source Type: research