Genome-wide association identifies a novel locus for delirium risk

We aimed to identify common genetic variations associated with delirium through genome-wide association testing in a hospital biobank. We applied a published electronic health record based definition of delirium to identify cases of delirium, and control individuals with no history of delirium, from a biobank spanning two Boston academic medical centers. Among 6,035 individuals of Northern European ancestry, including 421 with a history of delirium, we used logistic regression to examine genome-wide association.

Source: Neurobiology of Aging - March 9, 2018 Category: Neuroscience Authors: Thomas H. McCoy, Kamber Hart, Amelia Pellegrini, Roy H. Perlis Source Type: research