Synthetic addiction extends the productive life time of engineered Escherichia coli populations [Applied Biological Sciences]
Bio-production of chemicals is an important driver of the societal transition toward sustainability. However, fermentations with heavily engineered production organisms can be challenging to scale to industrial volumes. Such fermentations are subject to evolutionary pressures that select for a wide range of genetic variants that disrupt the biosynthetic capacity of...
Source: Proceedings of the National Academy of Sciences - Category: Science Authors: Peter Rugbjerg, Kira Sarup-Lytzen, Mariann Nagy, Morten Otto Alexander Sommer Tags: Biological Sciences Source Type: research