Allergists' use of epinephrine for food-induced anaphylaxis

The current food allergy epidemic and recent focus on early introduction of peanut has led many allergists to perform more oral food challenges (OFCs).1 Foods are the most common trigger of anaphylaxis in children, and as such, we are seeing an increase in severe reactions.2 It is not controversial that epinephrine is the treatment of choice for anaphylaxis.3 Since the term was first used in 1901, the definition of anaphylaxis has been controversial and only more recently well-defined as “a severe, potentially fatal, systemic allergic reaction that occurs suddenly after contact with an allergy-causing substance.”4 This definition, however, does nothing to help the physician diagnose anaphylaxis and initiate proper treatment.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Source Type: research