Altered intestinal microbiota and blood T cell phenotype are shared by patients with Crohn's disease and their unaffected siblings

Conclusions
Healthy siblings of patients with CD manifest immune and microbiological abnormalities associated with CD distinct from their genotype-related risk and provide an excellent model in which to investigate early CD pathogenesis.

Source: Gut - September 2, 2014 Category: Gastroenterology Authors: Hedin, C. R., McCarthy, N. E., Louis, P., Farquharson, F. M., McCartney, S., Taylor, K., Prescott, N. J., Murrells, T., Stagg, A. J., Whelan, K., Lindsay, J. O. Tags: Crohn's disease Inflammatory bowel disease Source Type: research