Global Health: Measles Cases in Europe Quadrupled in 2017

Outbreaks across the continent infected 21,000 and killed at least 35 people. Now governments are moving to make vaccinations mandatory.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Epidemics Measles Vaccination and Immunization Romani People Centers for Disease Control and Prevention London School of Hygiene and Tropical Medicine World Health Organization Europe Source Type: news

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In conclusion, we demonstrated a simple generation-dependent model that was able to adequately capture an observed transmission pattern of the measles outbreak in Japan, 2018. The proposed model also helped predict the future incidence and evaluate public health control measures. Polishing the forecasting model further, we can achieve an eventual routine forecast and evaluation the outbreaks while maintaining the model structure as simple as possible. Competing Interests The authors declare no competing interests. Data Availability The code snippets used for simulations and generation of figures as well as the epidemiolo...
Source: PLOS Currents Outbreaks - Category: Epidemiology Authors: Source Type: research
This study was to verify the existence and extent of mumps outbreak in Copperbelt province; to describe the epidemiological characteristics of the outbreak; to identify risk factors associated with the illness; to confirm the etiology of the outbreak through appropriate laboratory testing; to inform disease control strategy and advocate for mumps, measles and rubella vaccine in Zambia, which has not yet been implemented.Study designA case report. Clinical records of cases suspected of mumps in the district were reviewed. Cases covered the first 36 weeks of 2015 (January to September, 2015). Charts were generated to capture...
Source: Clinical Epidemiology and Global Health - Category: Epidemiology Source Type: research
Publication date: 2018Source: Advances in Virus Research, Volume 100Author(s): Kristin Pfeffermann, Mareike Dörr, Florian Zirkel, Veronika von MesslingAbstractDespite the availability of safe and effective vaccines against measles and several animal morbilliviruses, they continue to cause regular outbreaks and epidemics in susceptible populations. Morbilliviruses are highly contagious and share a similar pathogenesis in their respective hosts. This review provides an overview of morbillivirus history and the general replication cycle and recapitulates Morbillivirus pathogenesis focusing on common and unique aspects se...
Source: Advances in Virus Research - Category: Virology Source Type: research
Publication date: Available online 1 February 2018Source: Microbes and InfectionAuthor(s): Phanramphoei N. Frantz, Samaporn Teeravechyan, Frédéric TangyAbstractInfectious disease epidemics match wars and natural disasters in their capacity to threaten lives and damage economies. Like SARS previously and Zika recently, the Ebola crisis in 2015 showed how vulnerable the world is to these epidemics, with over 11,000 people dying in the outbreak. In addition to causing immense human suffering, these epidemics particularly affect low- and middle-income countries. Many of these deadly infectious diseases that have ...
Source: Microbes and Infection - Category: Infectious Diseases Source Type: research
Publication date: 2018Source: Advances in Virus Research, Volume 100Author(s): Kristin Pfeffermann, Mareike Dörr, Florian Zirkel, Veronika von MesslingAbstractDespite the availability of safe and effective vaccines against measles and several animal morbilliviruses, they continue to cause regular outbreaks and epidemics in susceptible populations. Morbilliviruses are highly contagious and share a similar pathogenesis in their respective hosts. This review provides an overview of morbillivirus history and the general replication cycle and recapitulates Morbillivirus pathogenesis focusing on common and unique aspects se...
Source: Advances in Virus Research - Category: Virology Source Type: research
ud JM Abstract Madagascar reports few measles cases annually and high vaccination campaign coverage. However, the underlying age profile of immunity and risk of a measles outbreak is unknown. We conducted a nested serological survey, testing 1,005 serum collected between November 2013 and December 2015 via Madagascar's febrile rash surveillance system, for measles immunoglobulin G antibody titers. We directly estimated the age profile of immunity and compared these estimates to indirect estimates based on a birth cohort model of vaccination coverage and natural infection. Combining these estimates of the age profi...
Source: Am J Epidemiol - Category: Epidemiology Authors: Tags: Am J Epidemiol Source Type: research
PHE claims travel between European countries experiencing measles epidemics is behind England's outbreak, as well as people failing to take up the recommended MMR vaccines.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
PHE claims travel between European countries experiencing measles epidemics is behind England's outbreak, as well as people failing to take up the recommended MMR vaccines.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Conclusions: School vacations are associated with greatly reduced overall measles transmission. However, transmission is not eliminated, and increased long-distance travel may even promote spread to other areas. Therefore, we estimate that school closure is unlikely to prevent measles epidemics unless there are still few cases and the community is well vaccinated.
Source: Epidemiology - Category: Epidemiology Tags: Infectious diseases Source Type: research
In conclusion, the simplistic generation-dependent model was demonstrated to capture the observed dynamics of measles outbreaks, helping to predict the future and evaluate public health control. Polishing the forecasting model further, we aim to achieve an eventual routine forecasting and evaluation of measles, while maintaining the model structure as simple as possible.
Source: PLOS Currents Outbreaks - Category: Epidemiology Authors: Source Type: research
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