Two ‐year trial of intermittent insulin therapy vs metformin for the preservation of β‐cell function after initial short‐term intensive insulin induction in early type 2 diabetes

ConclusionAfter induction IIT, metformin was superior to intermittent IIT for maintaining β‐cell function and glycaemic control over 2 years. The strategy of induction and maintenance therapy to preserve β‐cell function warrants exploration in early T2DM.

Source: Diabetes, Obesity and Metabolism - February 23, 2018 Category: Endocrinology Authors: Ravi Retnakaran, Haysook Choi, Chang Ye, Caroline K. Kramer, Bernard Zinman Tags: ORIGINAL ARTICLE Source Type: research