AMPK/Nrf2 signaling is involved in the anti-neuroinflammatory action of Petatewalide B from Petasites japonicus against lipopolysaccharides in microglia.

CONCLUSIONS: Our findings provide the possible mechanism of the anti-neuroinflammatory properties of Petatewalide B that result from beneficial responses in the AMPK/Nrf2-signaling pathway. PMID: 29433360 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/29433360?dopt=Abstract

Source: Immunopharmacology and Immunotoxicology - February 14, 2018 Category: Allergy & Immunology Tags: Immunopharmacol Immunotoxicol Source Type: research