Bacteriology and cefuroxime-resistance in endophthalmitis following cataract surgery before and after the introduction of prophylactic intracameral cefuroxime: a retrospective single-centre study

Conclusions Intracameral cefuroxime achieves a reduction of the rate of endophthalmitis after cataract surgery and brings about a shift in pathogens from cefuroxime sensitive to cefuroxime resistant organisms.
Source: Journal of Hospital Infection - Category: Infectious Diseases Source Type: research

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Erica S. Tarabadkar† and Michi M. Shinohara*† Division of Dermatology, University of Washington, Seattle, WA, United States Skin directed therapies (SDTs) serve important roles in the treatment of early stage cutaneous T-cell lymphoma (CTCL)/mycosis fungoides (MF), as well as managing symptoms and improving quality of life of all stages. There are now numerous options for topical therapies that demonstrate high response rates, particularly in early/limited MF. Phototherapy retains an important role in treating MF, with increasing data supporting efficacy and long-term safety of both UVB and PUVA as ...
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
Chances are high that most of us will have a surgical procedure at some point during our lives. Estimates based on 2002 data in three states suggest Americans have a lifetime average of nine surgical procedures. In 2010 in the United States, there were an estimated 1.4 million inpatient procedures, ranging from childhood tonsillectomies, breast lumpectomies, and gallbladder removal to cataract surgeries, hernia repairs, and hip or knee replacements. And the rate of surgical procedures continues to rise. So it’s valuable to know what you can do to make safer surgery and a successful outcome more likely. How do I choos...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Health Managing your health care Safety Surgery Source Type: blogs
Publication date: January 2019Source: Journal of Hospital Infection, Volume 101, Issue 1Author(s): E. Friling, P. MontanSummaryBackgroundIntracameral cefuroxime as prophylaxis against postoperative endophthalmitis (POE) following cataract surgery was introduced in 1996 at St Erik Eye Hospital. Soon after the introduction of intracameral cefuroxime, the rate of POE fell dramatically and a shift in the aetiology was noticed.AimTo analyse bacteriology and susceptibility to cefuroxime before and after the introduction of intracameral cefuroxime.MethodsAll culture-proven cases of endophthalmitis at St Erik Eye Hospital after ca...
Source: Journal of Hospital Infection - Category: Infectious Diseases Source Type: research
Abstract Endophthalmitis, an inflammation of the eye due to perioperative infection, may occur after cataract surgery. Intraocular lenses (IOLs) loaded with an antibiotic have been proposed as an alternative to the conventional postoperative endophthalmitis prophylaxis, since the antibiotic is delivered directly to the target site. In this work, an IOL-based antibiotic releasing system was prepared from a copolymer used in the production of IOLs and a fluoroquinolone used in endophthalmitis prophylaxis (moxifloxacin, MFX). Argon plasma-assisted grafting with 2-hydroxyethyl methacrylate (HEMA) in the presence of MF...
Source: European Journal of Pharmaceutics and Biopharmaceutics - Category: Drugs & Pharmacology Authors: Tags: Eur J Pharm Biopharm Source Type: research
ConclusionIn cataract surgery, irrigation every 20 seconds of the operative field with 0.025% PI or 0.0025% PAI, both of which contain 0.0025% available iodine concentration, achieved a very low bacterial contamination rate in the anterior chamber.
Source: Acta Ophthalmologica - Category: Opthalmology Authors: Tags: Original Article Source Type: research
We report a case of keratitis associated with limbal relaxing incision (LRI). The patient presented with progressive loss of vision with best-corrected visual acuity 20/40. Immature cataract with 1.43D against the rule astigmatism was noted. Prophylactic topical antibiotic was administered before surgery. He underwent uneventful phacoemulsification with intraocular lens implantation with LRI. On the 33rd postoperative day (POD), he presented with infiltrate along LRI site with mild iritis. Corneal scraping was positive for Staphylococcus aureus. After the treatment with topical moxifloxacin and fortified cefazolin, the inf...
Source: Indian Journal of Ophthalmology - Category: Opthalmology Authors: Source Type: research
In this report, an infant with successful cataract surgery after elimination of the organism is presented.[J Pediatr Ophthalmol Strabismus. 2016;53:e29 –e31.]
Source: Journal of Pediatric Ophthalmology and Strabismus - Category: Opthalmology Source Type: research
Conclusions In the current study, visual acuity outcomes were generally poor. Enterococcus and Staphylococcus species were the most common organisms reported and postoperative endophthalmitis after cataract surgery was the most common clinical setting.
Source: British Journal of Ophthalmology - Category: Opthalmology Authors: Tags: Ophthalmologic surgical procedures, Choroid, Eye (globe), Lens and zonules Review Source Type: research
A 79-year-old woman had uneventful femtosecond laser–assisted cataract surgery including paired laser astigmatic keratotomies (AKs) in the right eye. Three weeks postoperatively, a corneal infiltrate developed in the superotemporal AK incision. Cultures grew methicillin-resistant Staphylococcus aureus. The infection was treated with topical fortified vancomycin and tobramycin; full resolution required several months of therapy. Five months after cataract surgery, the patient presented with a second stromal infiltrate, also in the superotemporal AK incision.
Source: Journal of Cataract and Refractive Surgery - Category: Opthalmology Authors: Tags: Case report Source Type: research
Acute post-cataract surgery endophthalmitis is almost always caused by bacteria, although less commonly, fungi and mycobacteria have also been reported as agents of the infection. With an estimated incidence of 0.06 to 0.3%, endophthalmitis is the most serious complication of intraocular surgery, because it may result in a severe decrease of visual acuity or even blindness in the involved eye (1–5). In Western countries, coagulase-negative staphylococci are responsible for 70% of post-cataract endophthalmitis, followed by Staphylococcus aureus, viridans group streptococci, and other gram-positive bacteria.
Source: Clinical Microbiology Newsletter - Category: Microbiology Authors: Tags: Case Report Source Type: news
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