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New study explains how your brain helps you learn new skills

(Gladstone Institutes) Researchers from the Gladstone Institutes uncovered how a special type of neuron improves the efficiency of procedural learning. They initially wanted to show how the specialized brain cells, called fast-spiking interneurons, cause movement disorders, such as Tourette's syndrome, dystonia, and dyskinesia. As it turns out, that isn't the case. But their work led them to an even greater discovery.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news

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Angelo Quartarone, Diane Ruge
Source: Frontiers in Neurology - Category: Neurology Source Type: research
No abstract available
Source: Neurology Today - Category: Neurology Tags: Features Source Type: research
Feixia Zheng, Xiuyun Ye, Xulai Shi, Neha Devi Poonit, Zhongdong Lin
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Conclusions Overall, these findings suggest that a critical factor in TS treatment should involve modulation of both frontostriatal and motor networks, rather than be treated as a focal disorder of the brain. Using the novel combination of DBS-evoked tic reduction and fMRI in human subjects, we provide new insights into the basal ganglia-cerebellar-thalamo-cortical network-level mechanisms that influence the effects of thalamic DBS. Future translational research should identify whether these network changes are cause or effect of TS symptoms.
Source: NeuroImage: Clinical - Category: Radiology Source Type: research
Neuropediatrics DOI: 10.1055/s-0037-1618590Child bilateral striatal necrosis (BSN) is a rare and etiologically heterogeneous condition. An association with group A streptococcus (GAS) infection was previously reported in two cases of BSN in infancy and early childhood. We here report on a 7-year-old boy who developed chorea and dystonia 20 days after symptomatic recovery from Sydenham's chorea. Repeated brain magnetic resonance imaging scans, obtained before, soon after the onset of the post-Sydenham symptoms, and 1 year later were consistent with an evolution from bilateral striatal microbleeding to necrosis, and c...
Source: Neuropediatrics - Category: Neurology Authors: Tags: Short Communication Source Type: research
Neuropediatrics DOI: 10.1055/s-0038-1626709 Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Full text
Source: Neuropediatrics - Category: Neurology Authors: Tags: Videos and Images in Neuropediatrics Source Type: research
AbstractA movement disorder emergency has been defined by Fahn and Frucht as “any neurological disorder evolving acutely or subacutely, in which the clinical presentation is dominated by a primary movement disorder, and in which failure to accurately diagnose and manage the patient may result in significant morbidity or even mortality.” In this review, we discuss the mos t common situations in which hyperkinetic movement disorders, including chorea, ballism, dystonia, myoclonus, tics, as well as psychogenic disorders, can present as emergencies. Some acute hyperkinetic issues that can complicate Parkinson&rsquo...
Source: Current Neurology and Neuroscience Reports - Category: Neuroscience Source Type: research
New treatment for Tourette's Tics are common and may present to both paediatric and child psychiatry clinics. For most, reassurance and advice are all that is needed, but for a few they can become seriously disabling and may progress to Tourette's syndrome. Treatment with antipsychotic drugs such as Haloperidol is effective, but can severe side-effects such as sedation, dystonia and tardive dyskinesia. Newer ‘atypical’ antipsychotic drugs are being used increasingly in schizophrenia as they appear to be better tolerated. One such is Aripiprazole: researchers from Jiangsu, China set out to review the literature ...
Source: Archives of Disease in Childhood - Category: Pediatrics Tags: Miscellanea Source Type: research
Authors: di Biase L, Munhoz RP Abstract INTRODUCTION: Deep brain stimulation effectiveness is well recognized for different movement disorders including Parkinson's disease, dystonia and essential tremor, however several other diseases in this field may benefit from the technique although experience is sparse and evidences of benefit and risks are not established. AREAS COVERED: In this review, we explored available evidence for effectiveness and safety of DBS in selected hyperkinetic movement disorders, including tardive dyskinesia, Huntington's disease, neuroacanthocytosis, myoclonus-dystonia, Tourette syndro...
Source: Expert Review of Neurotherapeutics - Category: Neurology Tags: Expert Rev Neurother Source Type: research
Conclusions: AEs following pvGPi DBS in refractory TS were mostly related to stimulation or hardware, but did not limit therapy. Controlled studies are warranted.Disclosure: Dr. Niemann has nothing to disclose. Dr. Strutt has received personal compensation for activities with Psychology Software Tools as a consultant. Dr. Viswanathan has nothing to disclose. Dr. Jimenez Shahed has received personal compensation for activities with Teva as a consultant. Dr. Jimenez Shahed has received research support from Avid Radiopharmaceutical, Inc., Acadia Pharmaceuticals, US World Meds, and Biotie.
Source: Neurology - Category: Neurology Authors: Tags: Movement Disorders: Tics, Tourette ' s Syndrome, and Other Source Type: research
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