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NIH inks $5m partnership with PathMaker Neurosystems for MyoRegulator spasticity device

PathMaker Neurosystems said today it signed a $5 million cooperative partnership deal with the National Institutes of Health to support continued development of its MyoRegulator neurostimulation system designed to treat spasticity secondary to stroke. The MyoRegulator device, based on PathMaker’s DoubleStim technology, is designed to provide simultaneous, non-invasive stimulation at spinal and peripheral locations, the Boston and Paris-based company said. The money comes as part of a four-year grant awarded through the CREATE Devices program which also provides a partnership with the NIH’s National Institute of Neurological Disorders and Stroke, PathMaker said. “We are truly honored and delighted to receive this support from NINDS to advance our breakthrough non-invasive neuromodulation technology that can benefit many patients in desperate need of treatment options. This collaborative partnership and funding will support product engineering, multi-center U.S. pivotal trials and regulatory submission for MyoRegulator,” prez &CEO Dr. Nader Yaghoubi said in a press release. “The CREATE Devices program encourages the pursuit of translational and clinical studies for innovative therapeutic devices to treat neurological disorders,” NINDS program director Nick Langhals said in a prepared statement. Last February, PathMaker Neurosystems said that it won a grant from BpiFrance to support its MyoRegulator neurostim device. The pos...
Source: Mass Device - Category: Medical Devices Authors: Tags: Business/Financial News Neuromodulation/Neurostimulation PathMaker Neurosystems Inc. Source Type: news

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Source: BMJ Comments - Category: General Medicine Source Type: forums
Authors: de Gregorio C Abstract Regardless of advances in medical and interventional treatment of cardiovascular disease (CVD), a limited number of patients attend a cardiac rehabilitation (CR) programme on a regular basis. Due to modern therapies more individuals will be surviving an acute cardiovascular event, but the expected burden of chronic heart failure will be increasing worldwide.However, both in high- and low-income countries, secondary prevention after an acute myocardial infarction or stroke has been implemented in less than a half of eligible patients.Combined interventions are still needed to reduce d...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Authors: Gale RP, Hochhaus A Abstract Chronic myeloid leukemia (CML) can be cured using tyrosine kinase-inhibitors (TKIs) when cure is defined as achieving a life-expectancy similar or even better than sex- and age-matched persons without CML. Most deaths in persons with CML are now from non-leukemia-related causes including heart disease, diabetes other cancers and stroke. Contrary to expectation, 40-50 percent of persons with CML treated for a few years with TKIs and who achieve a deep molecular response can stop TKI-therapy without leukemia recurrence for several years, some possibly indefinitely. Consequently, ...
Source: Expert Review of Hematology - Category: Hematology Tags: Expert Rev Hematol Source Type: research
CONCLUSIONS: To our knowledge, this is the first study to explore the effects of CRP on PSCI in Han Chinese with ICAS. Our findings indicate that higher CRP levels at admission are associated with subsequent cognitive decline in Han Chinese patients with ICAS following ischemic stroke. Further studies in other ethnic groups are needed to validate the use of CRP to predict dementia in ICAS patients. PMID: 29451096 [PubMed - as supplied by publisher]
Source: Neurological Research - Category: Neurology Tags: Neurol Res Source Type: research
Viz.Ai has just received Food and Drug Administration (FDA) clearance to market its artificial intelligence application that can alert a neurovascular specialist if their patient is possibly suffering a stroke. When the app detects large vessel blockage, it sends the physician a text message who can then review the patient ’s brain images at their computer station. This alert system can expedite treatment procedures and potentially delay the stroke’s progression. More young adults are being hospitalized for strokes. Although there has been an increase in stroke survival rates,as of 2013, stroke is the fifth lea...
Source: radRounds - Category: Radiology Authors: Source Type: blogs
CONCLUSIONS: Addition of carotid ultrasonography measures to conventional risk factors significantly improved the stratification of patients by cardiovascular risk. Changes over time in carotid ultrasonography measures may be used as therapeutic outcome measures. PMID: 29445076 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - Category: Cardiology Tags: J Atheroscler Thromb Source Type: research
SATURDAY, Feb. 17, 2018 -- Strokes in babies may not have the same lasting effects as they do in adults, a new study suggests. Researchers from the Georgetown University Medical Center found that people who'd had a stroke as a newborn that damaged...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
Authors: Boggs JM, Beck A, Hubley S, Peterson EL, Hu Y, Williams LK, Prabhakar D, Rossom RC, Lynch FL, Lu CY, Waitzfelder BE, Owen-Smith AA, Simon GE, Ahmedani BK Abstract OBJECTIVE: Mitigation of suicide risk by reducing access to lethal means, such as firearms and potentially lethal medications, is a highly recommended practice. To better understand groups of patients at risk of suicide in medical settings, the authors compared demographic and clinical risk factors between patients who died by suicide by using firearms or other means with matched patients who did not die by suicide (control group). METHODS: I...
Source: Psychiatric Services - Category: Psychiatry Tags: Psychiatr Serv Source Type: research
(Georgetown University Medical Center) A stroke in a baby -- even a big one -- does not have the same lasting impact as a stroke in an adult. A study led by Georgetown University Medical Center investigators found that a decade or two after a 'perinatal' stroke damaged the left 'language' side of the brain, affected teenagers and young adults used the right sides of their brain for language.
Source: EurekAlert! - Social and Behavioral Science - Category: International Medicine & Public Health Source Type: news
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