Dopamine D1 receptor positive neurons in the lateral nucleus of the cerebellum contribute to cognitive behavior

Studies in humans and non-human primates have identified a region of the dentate nucleus of the cerebellum (DCN), or lateral nucleus in rodents (LCN), activated during performance of cognitive tasks involving complex spatial and sequential planning. Whether such a subdivision exists in the rodent is not known. Dopamine and its receptors, which are implicated in cognitive function, are present in the cerebellar nuclei but their function is unknown.

Source: Biological Psychiatry - February 3, 2018 Category: Psychiatry Authors: Timothy M. Locke, Marta E. Soden, Samara M. Miller, Avery Hunker, Cerise Knakal, Julia A. Licholai, Karn S. Dhillon, C. Dirk Keene, Larry S. Zweifel, Erik S. Carlson Tags: Priority Communication Source Type: research