Insula-Retrosplenial Cortex Overconnectivity Increases Internalizing Via Reduced Insight in Autism

Internalizing symptoms like anxiety and depression are common and impairing in autism spectrum disorder (ASD). Here, we test the hypothesis that aberrant functional connectivity between three brain networks [salience network (SN), default-mode network (DMN), and frontoparietal network (FPN)] plays a role in the pathophysiology of internalizing in ASD.

Source: Biological Psychiatry - February 3, 2018 Category: Psychiatry Authors: Jeremy Hogeveen, Marie K. Krug, Matthew V. Elliott, Marjorie Solomon Tags: Archival Report Source Type: research