Dimensionality and Reliability of the Central Sensitization Inventory in a Pooled Multicountry Sample

Central sensitization (CS) has been defined as an amplification of neural signaling within the central nervous system, which evokes pain hypersensitivity.51 CS has been proposed as an underlying mechanism for many pain-related conditions, including fibromyalgia, irritable bowel syndrome, temporomandibular joint disorder, headache, and spinal pain disorders.6,21,39,48,56 CS-related pain disorders often share other common secondary symptoms, such as insomnia, feeling “unrefreshed” after sleeping, difficulty concentrating, and fatigue.

Source: The Journal of Pain - November 30, 2017 Category: Materials Science Authors: Antonio I. Cuesta-Vargas, Randy Neblett, Alessandro Chiarotto, Jeroen Kregel, Jo Nijs, C. Paul van Wilgen, Laurent Pitance, Aleksandar Knezevic, Robert J. Gatchel, Tom G. Mayer, Carlotta Viti, Cristina Roldan-Jim énez, Marco Testa, Wolnei Caumo, Milica J Tags: Original Report Source Type: research