Reduced Fertility Potential in Young Patients Following Hematopoietic Stem Cell Transplantation Despite Reduced Intensity Conditioning

Background: Reduced intensity conditioning (RIC) is increasingly used for hematopoietic stem cell transplantation (HCT). Risk of infertility and primary gonadal insufficiency secondary to standard myeloablative (MAC) HCT is high, but little is known of these complications following use of RIC HCT.

Source: Biology of Blood and Marrow Transplantation - February 1, 2018 Category: Hematology Authors: Helen Oquendo-del Toro, Jonathan C. Howell, Priscila Badia, Janie Benoit, Stella M. Davies, Michael S. Grimley, Sonata Jodele, Christine Phillips, Karen Burns, Pooja Khandelwal, Javier El-Bietar, Rebecca A. Marsh, Adam S. Nelson, Gregory Wallace, Christop Source Type: research