Protective effects of flagellin A N/C against radiation-induced NLR pyrin domain containing 3 inflammasome-dependent pyroptosis in intestinal cells

Radiation-induced enteropathy is among the most prevalent dose-limiting radiation toxicities. Despite its prevalence and burden, there are currently no effective treatments for radiation-induced intestinal injury, and understanding of this pathology remains poor. The present study aimed to investigate changes induced in mouse intestines after irradiation and to explore the potential radioprotective effects of flagellin A (FlaA) N/C.

Source: International Journal of Radiation Oncology * Biology * Physics - January 21, 2018 Category: Radiology Authors: Dongming Wu, Rong Han, Shihua Deng, Teng Liu, Ting Zhang, Hongxiang Xie, Ying Xu Tags: Biology Contribution Source Type: research