Clinico-serologic features of statin-induced necrotising autoimmune myopathy in a single-centre cohort

We report a novel a ssociation of anti-HMGCR antibodies with truncal weakness in patients with statin-induced NAM. Functional impairments persist despite normalisation of muscle strength. Anti-HMGCR antibodies may disappear with treatment, paralleled by clinical remission of disease. Further prospective clinical trials are needed to determine optimal management strategies for statin-induced NAM.
Source: Clinical Rheumatology - Category: Rheumatology Source Type: research