Inflammatory back pain and associated disease conditions among patients with chronic low back pain in Bangladesh
In this study, we estimated the prevalence of IBP and the subtypes of SpA in a tertiary hospital in Bangladesh. MethodsThis 1 year cross‐sectional study was conducted among 240 CLBP patients in a rheumatology outpatient clinic. Assessment of Spondyloarthritis International Society classification criteria of IBP and predefined recognized classification criteria were followed to define different subtypes of SpA. Means and standard deviations were reported for continuous variables. Descriptive and bi‐variate analyses were accordingly performed. ResultsOf 240 CLBP patients, 60 (25%) had IBP and 180 (75%) had mechanical back pain (MBP). Among the 60 IBP patients, 52 (86.6%) had predominantly axial SpA (axSpA) and eight (13.4%) had predominantly peripheral spondyloarthritis. In the axSpA group, 49 (94.2%) had radiographic axSpA (rd‐axSpA) also known as AS and three (5.8%) had non‐radiographic axSpA (nr‐axspA). AxSpA patients could be divided into eight (15.35%) with psoriasis, two (3.8%) with reactive arthritis and one patient (1.9%) had arthritis associated with inflammatory bowel disease. Fifty (83.3%) IBP and 73 (40.6%) MBP patients had age at onset of back pain
Dysregulated intestinal epithelial apoptosis initiates gut injury, alters the intestinal barrier, and can facilitate bacterial translocation leading to a systemic inflammatory response syndrome (SIRS) and/or multi-organ dysfunction syndrome (MODS). A variety of gastrointestinal disorders, including inflammatory bowel disease, have been linked to intestinal apoptosis. Similarly, intestinal hyperpermeability and gut failure occur in critically ill patients, putting the gut at the center of SIRS pathology. Regulation of apoptosis and immune-modulatory functions have been ascribed to Thirty-eight-negative kinase 1 (TNK1), whos...
Adult scoliosis is different from the type children like Princess Eugenie develop - as Roger Neuberg, 77, from Leicester,experienced first-hand. This is his story.
HOW to sleep: Sleep better by having a good bedtime routine, watching your diet, or by avoiding back pain-causing mattresses. Avoid eating this fruit before you go to bed, or risk a bad night ’s sleep.
Conclusions: An early decrease in F-CPT levels in children with newly diagnosed active luminal CD did not predict clinical response at week 6 of EEN induction therapy, and clinical remission was predicted with low accuracy. Therefore, F-CPT cannot be used as a predictor to select the patients in whom EEN should be terminated.What is Known:•The fecal calprotectin (F-CPT) is an important marker of intestinal inflammation.•Approximately 25% of pediatric patients with Crohn disease (CD) do not achieve clinical remission, and there is still no sufficient predictor of response to exclusive enteral nutrition (EEN) treat...
(MedPage Today) -- Meta-analysis reports mild reductions in spasticity, pain, bladder dysfunction
Probiotics and fecal microbiota transplantation are effective for clinical remission and clinical response in ulcerative colitis, a meta-analytic review suggests.Medscape Medical News
(MedPage Today) -- Palindromic rheumatism was characterized by extracapsular inflammation
The survey, of more than 500 patients scheduled for surgery, found that more than three-quarters expected to get opioids afterward. Most also thought opioids were the most effective treatment for post-surgery pain.
Following a difficult surgery, some patients end up experiencing cognitive decline and delirium, which seems to arise from inflammatory changes in the brain, that are still poorly understood. This inflammation is difficult to control in a targeted wa...
ConclusionsOur study suggests that burn survivors and front-line burn providers have similar views on what constitutes an ideal dressing. A significantly proportion of caregiver/survivors felt that pain associated with dressing changes is being adequately managed despite healthcare providers’ perception.