Bax inhibitor-1 is required for resisting the Early Brain Injury induced by subarachnoid hemorrhage through regulating IRE1-JNK pathway.

Conclusion Our results indicate that BI-1 may participate in the regulation of EBI after SAH by regulating IRE1-JNK pathway. Thus, the results suggest that BI-1 may be a potential therapeutic target for SAH treatment. PMID: 29334839 [PubMed - as supplied by publisher]
Source: Neurological Research - Category: Neurology Tags: Neurol Res Source Type: research