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Risk Factors for Ventilator-Associated Events in a PICU*

Objective: The term ventilator-associated events includes ventilator-associated condition, infection-related ventilator-associated complication, and ventilator-associated pneumonia. We sought to identify potential new risk factors for ventilator-associated condition and infection-related ventilator-associated complication in the PICU population. Design: Matched case control study. Setting: Children’s hospital at a tertiary care academic medical center. Patients: During the study period, 606 patients were admitted to PICU and ventilated more than 48 hours; 70 children met ventilator-associated condition criteria. Interventions: None. Measurements and Main Results: We applied the definition for ventilator-associated condition (i.e., a sustained increase in ventilator settings after a period of stable or decreasing support) to our database. Within ventilator-associated condition cases, 40 cases were infection-related ventilator-associated complication and 30 cases were noninfectious-related ventilator-associated condition. We identified 140 controls and matched to ventilator-associated condition cases with regard to age, immunocompromised status, and ventilator days to event. Patients with ventilator-associated condition had longer ICU stay versus controls; 24 days median (12–43 interquartile range) versus 7 days (4–14); (p
Source: Pediatric Critical Care Medicine - Category: Pediatrics Tags: Online Clinical Investigations Source Type: research

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CONCLUSIONS: The most prevalent diagnosis in children with BD-resistant airflow limitation is asthma. Allergic rhinitis and premature birth are common co-morbidities. Children without a history of asthma, as well as those with asthma but no allergic rhinitis, had lower pulmonary function. Children with BD-resistant airflow limitation may represent a sub-group of children with persistent obstruction and high risk for life-long airway disease. PMID: 29771599 [PubMed - as supplied by publisher]
Source: Journal of Asthma - Category: Respiratory Medicine Tags: J Asthma Source Type: research
Authors: De Luca D PMID: 29774737 [PubMed - as supplied by publisher]
Source: Minerva Anestesiologica - Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research
Conditions:   Pneumonia;   Streptococcus Infection Intervention:   Sponsor:   Assiut University Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Neuromuscular disease frequently leads to dysphagia and difficulty managing secretions. Dysphagia may lead to medical complications, such as malnutrition, dehydration, aspiration pneumonia, and other pulmonary complications, as well as social isolation and reduced overall quality of life. This review provides an overview of dysphagia associated with neuromuscular disease in adults, along with a concise review of swallowing assessment and intervention options.
Source: Clinics in Chest Medicine - Category: Respiratory Medicine Authors: Source Type: research
Lung ultrasound finds more cases of pneumonia in children and young adults...Read more on AuntMinnie.comRelated Reading: Can AI diagnose pneumonia better than radiologists? AIUM: Lung US can handle diagnosis of pediatric pneumonia Most pediatric chest x-rays appear unnecessary DR tomo holds promise for fungal pneumonia surveillance H7N9 bird flu pneumonia scans show common imaging findings
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
Abstract Outbreaks associated with exposure to treated recreational water can be caused by pathogens or chemicals in venues such as pools, hot tubs/spas, and interactive water play venues (i.e., water playgrounds). During 2000-2014, public health officials from 46 states and Puerto Rico reported 493 outbreaks associated with treated recreational water. These outbreaks resulted in at least 27,219 cases and eight deaths. Among the 363 outbreaks with a confirmed infectious etiology, 212 (58%) were caused by Cryptosporidium (which causes predominantly gastrointestinal illness), 57 (16%) by Legionella (which causes Leg...
Source: MMWR Morb Mortal Wkl... - Category: Epidemiology Authors: Tags: MMWR Morb Mortal Wkly Rep Source Type: research
Felicity Cottle discusses the impact of sepsis and what trusts can do to continue improving early recognition and treatment Related items fromOnMedica New drive to reduce sepsis deaths unveiled Treat sepsis with same urgency as suspected heart attacks, clinicians told Emergency sepsis care improving but treatment still not given fast enough Pneumonia or sepsis linked to increased risk of CVD New drive to fight ‘silent killer’ sepsis
Source: OnMedica Views - Category: Primary Care Source Type: news
There is a growing body of evidence to support the utility of lung point-of-care ultrasound (POCUS) in pediatric patients with multiple pulmonary pathologies, particularly pneumonia. As we increase our use of lung POCUS for pediatric patients with respiratory complaints, we must be mindful of the normal anatomy and sonographic findings within the pediatric chest and aware of how to distinguish normal findings (e.g., thymus) from pathologic findings (e.g., consolidation).
Source: The Journal of Emergency Medicine - Category: Emergency Medicine Authors: Tags: Ultrasound in Emergency Medicine Source Type: research
We share the main concerns expressed by Funda Sungur Biteker et al. in the study called “A small pericardial effusion is a marker of complicated hospitalization in patients with community-acquired pneumonia”. We would like to congratulate the authors for the idea of carrying out this study. The main objective was to evaluate the frequency and prognostic of small pericardial effusio n in patients hospitalized for community-acquired pneumonia. The authors found that the presence of a small pericardial effusion is associated with adverse events and increased mortality in various clinical conditions.
Source: Journal of Critical Care - Category: Intensive Care Authors: Source Type: research
Abstract Pneumonia is a type of acute lower respiratory infection that is common and severe. The outcome of lower respiratory infection is determined by the degrees to which immunity is protective and inflammation is damaging. Intercellular and interorgan signaling networks coordinate these actions to fight infection and protect the tissue. Cells residing in the lung initiate and steer these responses, with additional immunity effectors recruited from the bloodstream. Responses of extrapulmonary tissues, including the liver, bone marrow, and others, are essential to resistance and resilience. Responses in the lung...
Source: Physiological Reviews - Category: Physiology Authors: Tags: Physiol Rev Source Type: research
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