Rheological Properties of Commercially Available Hyaluronic Acid Products in the United States for the Treatment of Osteoarthritis Knee Pain.

Conclusions: Due to the differences in rheological properties between IA-HA products, the universal assessment of these products as a class may not be appropriate. Instead, it may be more appropriate to assess each product individually. Future research should aim to link these differences in rheological properties to the differences in clinical efficacy seen across these IA-HA products. PMID: 29326532 [PubMed]
Source: Clinical Medicine Insights: Arthritis and Musculoskeletal Disorders - Category: Orthopaedics Tags: Clin Med Insights Arthritis Musculoskelet Disord Source Type: research

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Total hip arthroplasty (THA) remains the primary treatment intervention for end stage hip osteoarthritis, and while it has been established that it is generally successful at reducing pain and restoring function, it is known that some abnormalities in hip joint biomechanics can remain post-operatively. Sit to stand (Sit-Stand) is an important functional activity and previous studies have shown that in patients with hip arthritis, this task can become difficult for a number of reasons, including restricted range of movement, and can lead to patients offloading their affected limb [1].
Source: Gait and Posture - Category: Orthopaedics Authors: Tags: Short communication Source Type: research
This study set out to investigate the relationship between patient-related outcome measures (PROMs) and measurements obtained from gait analysis before and after PFA. There are currently no studies relating to gait analysis and PFA available in the literature
Source: Gait and Posture - Category: Orthopaedics Authors: Tags: Short communication Source Type: research
ConclusionOur study found evidence of reduced ACC grey matter volume in participants with hand arthritis that persisted after treatment with centrally acting analgesics pregabalin and duloxetine, respectively. The sustained changes observed in the ACC in our study could reflect the relatively short duration of treatment, or that the differences observed are irreversible volume changes due to chronic pain that are established over time.
Source: Rheumatology International - Category: Rheumatology Source Type: research
ConclusionHip pain patients with radiographs demonstrating minimal to no hip arthritis with and without hip deformity experience significant cofounding yet modifiable disorders of sleep and anxiety. If recognized early in presentation, treatment of insomnia and anxiety ultimately will improve outcomes for hip patients treated either conservatively or surgically for their hip disorder.Level of EvidenceII
Source: PMandR - Category: Rehabilitation Source Type: research
Publication date: July 2018Source: Pharmacology &Therapeutics, Volume 187Author(s): Angela Wang, Daniel J. Leong, Luis Cardoso, Hui B. SunAbstractArthritis is a chronic disease of joints. It is highly prevalent, particularly in the elderly, and is commonly associated with pain that interferes with quality of life. Because of its chronic nature, pharmacological approaches to pain relief and joint repair must be safe for long term use, a quality many current therapies lack. Nutraceuticals refer to compounds or materials that can function as nutrition and exert a potential therapeutic effect, including the relief of pain,...
Source: Pharmacology and Therapeutics - Category: Drugs & Pharmacology Source Type: research
Authors: Dauvissat J, Rizzo C, Lellouche H, Porterie J, Melac-Ducamp S, Locquet V, Travers V, Maillet B, Conrozier T Abstract Purpose: To assess safety and search predictive factors of efficacy of a single intra-articular injection of a mannitol-modified hyaluronic acid (HA) viscosupplement, in patients having trapeziometacarpal (TMC) osteoarthritis (OA). Methods: Patients with symptomatic TMC OA, not adequately relieved by analgesic therapy and/or by the use of a thumb splint, were included in a 3-month prospective multicentre open-label trial. All underwent plain radiographs with the Kapandji incidences allow...
Source: Clinical Medicine Insights: Arthritis and Musculoskeletal Disorders - Category: Orthopaedics Tags: Clin Med Insights Arthritis Musculoskelet Disord Source Type: research
Conclusions: These results are promising, and additional research with a larger sample size and longer follow-up is needed to further examine the treatment effectiveness of multiple BMC injections for knee osteoarthritis. PMID: 29977117 [PubMed]
Source: Clinical Medicine Insights: Arthritis and Musculoskeletal Disorders - Category: Orthopaedics Tags: Clin Med Insights Arthritis Musculoskelet Disord Source Type: research
Publication date: July 2018Source: Pharmacology &Therapeutics, Volume 187Author(s): Angela Wang, Daniel J. Leong, Luis Cardoso, Hui B. SunAbstractArthritis is a chronic disease of joints. It is highly prevalent, particularly in the elderly, and is commonly associated with pain that interferes with quality of life. Because of its chronic nature, pharmacological approaches to pain relief and joint repair must be safe for long term use, a quality many current therapies lack. Nutraceuticals refer to compounds or materials that can function as nutrition and exert a potential therapeutic effect, including the relief of pain,...
Source: Pharmacology and Therapeutics - Category: Drugs & Pharmacology Source Type: research
ConclusionHip pain patients with radiographs demonstrating minimal to no hip arthritis with and without hip deformity experience significant cofounding yet modifiable disorders of sleep and anxiety. If recognized early in presentation, treatment of insomnia and anxiety ultimately will improve outcomes for hip patients treated either conservatively or surgically for their hip disorder.Level of EvidenceII
Source: PMandR - Category: Rehabilitation Source Type: research
ARTHRITIS is a common joint disease that typically affects people over the age of 50. One type of the disease, osteoarthritis, can have a particular impact on the knee. Treatments are available to help suppress pain and inflammation, but what symptoms should you look out for to indicate you may have the condition?
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
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