Usefulness of Integrating Heart Failure Risk Factors Into Impairment of Global Longitudinal Strain to Predict Anthracycline Related Cardiac Dysfunction

The prediction of cancer therapeutics-related cardiac dysfunction (CTRCD) is an essential aspect of care for individuals who receive potentially cardiotoxic oncologic treatments. Certain clinical risk factors have been described for incident CTRCD, and measurement of left ventricular (LV) longitudinal strain by speckle tracking 2-dimensional echocardiography (2DE) is the best-validated myocardial mechanical imaging assessment to detect subtle changes in LV function during cancer treatment. However, the direct integration of clinical and imaging risk factors to predict CTRCD has not yet been extensively examined.

Source: The American Journal of Cardiology - January 12, 2018 Category: Cardiology Authors: M. Wesley Milks, Michael R. Velez, Nishaki Mehta, Abiodun Ishola, Thomas Van Houten, Vedat O. Yildiz, Raquel Reinbolt, Maryam Lustberg, Sakima A. Smith, David A. Orsinelli Source Type: research