A Vitamin B12 Conjugate of Exendin ‐4 Improves Glucose Tolerance Without Associated Nausea or Hypophagia in Rodents

ConclusionsThese novel findings highlight the potential clinical utility of B12‐Ex4 conjugates as possible future T2DM therapeutics with reduced incidence of adverse effects.

Source: Diabetes, Obesity and Metabolism - January 1, 2018 Category: Endocrinology Authors: Elizabeth G. Mietlicki ‐Baase, Claudia G. Liberini, Jayme L. Workinger, Ron L. Bonaccorso, Tito Borner, David J. Reiner, Kieran Koch‐Laskowski, Lauren E. McGrath, Rinzin Lhamo, Lauren M. Stein, Bart C. De Jonghe, George G. Holz, Christian L. Roth, Rob Tags: ORIGINAL ARTICLE Source Type: research