Treatment of chronic rhinosinusitis with dornase alfa in patients with cystic fibrosis: a systematic review

ConclusionTopical intranasal dornase appears to improve sinonasal symptoms in CF patients to a greater degree than saline alone. The impact on other outcomes is less clear. Larger studies are needed to fully elucidate the true efficacy of dornase alfa in the treatment of CRS in CF patients.

Source: International Forum of Allergy and Rhinology - January 11, 2018 Category: Allergy & Immunology Authors: Gopi B. Shah, Linde Keyzer, Joy A. Russell, Ashleigh Halderman Tags: ORIGINAL ARTICLE Source Type: research