Multiple sclerosis: Cholesterol crystals prevent regeneration in central nervous system

(Technical University of Munich (TUM)) Multiple Sclerosis is a chronic inflammatory disease of the central nervous system, in which the immune cells attack myelin sheaths. Regeneration of myelin sheaths is necessary for patients to recover from MS relapses. Nevertheless, the ability to regenerate decreases with age. A team from Technical University Munich has published an explanation in " Science " : Fat derived from myelin, which is not carried away rapidly enough by phagocytes can trigger chronic inflammation that in turn impedes regeneration.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news