Blood Levels of Caffeine May Help Diagnose Parkinson ’s (CME/CE)
(MedPage Today) -- Study finds decreased metabolites in early disease, regardless of caffeine consumption
Condition: Parkinson Disease Interventions: Other: the timed 360° turn test; Other: Berg Balance Scale; Other: Four Square Step Test; Other: Functional Reach Test; Other: Trunk Impairment Scale; Other: Timed Up and Go Test; Other: Hoehn and Yahr Scale; Other: Unified Parkinson's Disease Rating Scale Sponsor: Gazi University Not yet recruiting
MONDAY, July 16, 2018 -- Vitamin D does little to defend your brain against multiple sclerosis, Parkinson's disease or Alzheimer's disease, a new review shows. The finding is based on an analysis of more than 70 studies. " Our work counters an...
DFJ, a WuXi AppTech venture fund and others are sold on the San Francisco startup's work at the intersection of biology, chemistry and computer science.
Researchers found a possible treatment for heart damage cause by Parkinson's, after finding that an imaging method could reveal and allow for treatment evaluation.
Alice Zhang was a graduate student at UCLA when she decided that there was a tremendous opportunity to speed up the process of drug development. " We could start taking the guesswork out of drug discovery. "
DiscussionThis will be the first trial to target balance in people with PD with combined exergaming and a-tDCS. We hypothesise that improvements in balance, functional and neurophysiological outcome measures, and neurocognitive outcome measures will be greater and longer-lasting following concurrent exergaming and a-tDCS than in those receiving sham tDCS or usual care.Trial registrationAustralian New Zealand Clinical Trials Registry,ACTRN12616000594426). Registered on 9 May 2016.
AbstractPurposeOur aim was to investigate the relation between delta wave notching time (DwNt) and accessory pathway location in patients with Wolff-Parkinson-White (WPW) syndrome.MethodsThe retrospective study included 149 WPW patients who underwent ablation therapy. DwNt was defined as the duration between the initial point of QRS and the notching in the delta wave. DwNt was divided by QRS duration to obtain the delta wave index (Dwi).ResultsPatients with left-sided accessory pathway (AP) had significantly higher DwNt (p
AbstractMorality is a complex and versatile concept that necessitates the integrated activity of multiple interacting networks in the brain. Numerous cortical and subcortical areas, many of which are implicated in either emotional and cognitive control or Theory of Mind, are involved in the processing of moral behaviour. Different methods have been used to investigate various aspects of morality, which has lead to confusing and sometimes opposing results. Emotional, cognitive and personality changes have long been recognized in Parkinson ’s disease (PD) patients, suggesting a potential impact on moral aspects of beha...
AbstractCognition and gait appear to be closely related. The chronological interplay between cognitive decline and gait dysfunction is not fully understood. The aim of the present prospective study is investigating whether the dysfunction of specific gait parameters, during specific task and medication conditions, may predict subsequent cognitive impairment in Parkinson ’s disease (PD). We evaluated cognition and gait in 39 Parkinsonian patients at an initial assessment and after 3 years. Cognitive performance was evaluated with a neuropsychological battery designed to assess memory, executive/attention, and vis...
Parkinson's disease (PD) is a progressive neurodegenerative disorder accompanied by movement deficits with selective degeneration of dopaminergic neurons in the substantia nigra (SN). Recent studies indicate that early diagnosis of PD has important implications for the disease-modifying strategy for PD showing not only some dopaminergic neuronal damage but also non-motor symptoms, which occur several years before the onset of motor symptoms. However, studies on the relationship between non-motor symptoms and its underlying mechanisms from the early to the late phase of PD are unknown.