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Artificial lung dev Breethe raises $3m

Artificial lung developer Breethe raised approximately $3 million in an equity financing round, according to an SEC filing posted late last month. Funds raised during the round will cover the sales and issuance of Series Seed-4 preferred stock and the underlying common stock convertible from it, according to the filing. The Baltimore-based company is developing the Oxy-1 ambulatory artificial lung system which is designed for home use for patients who suffer from acute and chronic lung failure, according to its website. The system includes a portable pack, which contains the unit’s batteries, oxygen source and pump motor and controller, a pump-lung unit which it anticipates will need to be replaced every 30 days and a blood cannula connection to the heart. Breethe was formed in 2014 as a spin-out from the University of Maryland, Baltimore, utilizing licensed technology from the University. A total of 22 anonymous investors joined the $3 million round, according to the filing, with the first sale date recorded on December 13. The company is not looking to raise any more funds in the round and hasn’t officially announced the round outside the SEC filing. The post Artificial lung dev Breethe raises $3m appeared first on MassDevice.
Source: Mass Device - Category: Medical Devices Authors: Tags: Business/Financial News Respiratory breethe Source Type: news

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In January, 2018, Academic Press published my bookPrecision Medicine and the Reinvention of Human Disease. This book has an excellent " look inside " at itsGoogle book site, which includes the Table of Contents. In addition, I thought it might be helpful to see the topics listed in the Book's index. Note that page numbers followed by f indicate figures, t indicate tables, and ge indicate glossary terms.AAbandonware, 270, 310geAb initio, 34, 48ge, 108geABL (abelson leukemia) gene, 28, 58ge, 95 –97Absidia corymbifera, 218Acanthameoba, 213Acanthosis nigricans, 144geAchondroplasia, 74, 143ge, 354geAcne, 54ge, 1...
Source: Specified Life - Category: Information Technology Tags: index jules berman jules j berman precision medicine Source Type: blogs
During 2017, the number of deceased organ donors in the United States topped 10,000 for the first time, according to preliminary data from United Network for Organ Sharing (UNOS), which serves as the national Organ Procurement and Transplantation Network (OPTN) under federal contract.  For the year, organs were recovered from 10,281 donors, representing a 3.1 percent increase over 2016 and an increase of 27 percent since 2007. A total of 34,768 organ transplants were performed in 2017 using organs from both deceased and living donors, according to preliminary data. This total is a 3.4 percent increase over 2016 and ma...
Source: blog.bioethics.net - Category: Medical Ethics Authors: Tags: Health Care syndicated Source Type: blogs
The purpose of this study was to describe the prevalence, characteristics and outcomes in pediatric patients with chromosomal anomalies (CA) undergoing orthotopic heart transplantation (OHT).
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Source Type: research
Given the shortage of suitable donor hearts for cardiac transplantation, and the favorable safety and efficacy of current agents used to treat hepatitis C (HCV), our institution recently piloted transplantation of selected patients using HCV-positive donors.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Source Type: research
Dr. Michael Peter Kaye, founding Member of the International Society for Heart and Lung Transplantation, Developer of the Society ’s Registry, and previous Editor of the Society’s Journal.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Source Type: research
Purpose of review The global shortage of organ donors will not be resolved solely by relying on deceased donation following a brain death determination (DBD). Expansion of deceased donation after circulatory death (DCD) will be needed to address the shortfall of organs for transplantation. Approximately 120 000 organ transplants are performed each year; however, the WHO estimates that this number of transplants only resolves 10% of the annual worldwide transplant need. Recent findings The report addresses the opportunity of DCD expansion by evaluating the DCD potential that is not being realized, the utility of DCD ...
Source: Current Opinion in Organ Transplantation - Category: Surgery Tags: COMPLICATIONS IN KIDNEY TRANSPLANTATION: Edited by Francis L. Delmonico Source Type: research
Conditions:   Acute Biphenotypic Leukemia;   Acute Lymphoblastic Leukemia in Remission;   Acute Myeloid Leukemia in Remission;   Blasts Under 10 Percent of Bone Marrow Nucleated Cells;   Blasts Under 5 Percent of Bone Marrow Nucleated Cells;   Chronic Myelogenous Leukemia, BCR-ABL1 Positive ;   Cytogenetic Abnormality;   High Risk Myelodysplastic Syndrome;   Myelodysplastic Syndrome With Excess Blasts;   Pancytopenia;   Refractory Anemia Interventions: &nb...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
We report the first application of ultra-deep sequencing (UDS) to varicella-zoster virus (VZV) genotypic antiviral testing in a case of acyclovir-resistant VZV infection initially detected by Sanger sequencing within a deeply immunocompromised heart transplant recipient. As added-value compared to Sanger analysis, UDS revealed complex dynamics of viral population under antiviral pressure. Varicella-zoster virus (VZV) is a ubiquitous human herpesvirus affecting populations worldwide. VZV is commonly acquired in youth whose primary infection usually manifests as benign varicella (chickenpox). After the initial infection, the...
Source: Antiviral Research - Category: Virology Authors: Tags: Antiviral Res Source Type: research
By HUGH HARVEY, MD Artificial intelligence requires data. Ideally that data should be clean, trustworthy and above all, accurate. Unfortunately, medical data is far from it. In fact medical data is sometimes so far removed from being clean, it’s positively dirty. Consider the simple chest X-ray, the good old-fashioned posterior-anterior radiograph of the thorax. One of the longest standing radiological techniques in the medical diagnostic armoury, performed across the world by the billions. So many in fact, that radiologists struggle to keep up with the sheer volume, and sometimes forget to read the odd 23,000 of the...
Source: The Health Care Blog - Category: Consumer Health News Authors: Tags: Uncategorized AI Data Hugh Harvey Radiology Source Type: blogs
Summary The effects of lung afferents denervation on cardiovascular regulation can be assessed on bilateral lung transplantation patients. The high‐frequency component of heart rate variability is known to be synchronous with breathing frequency. Then, if heart beat is neurally modulated by breathing frequency, we may expect disappearance of high frequency of heart rate variability in bilateral lung transplantation patients. On 11 patients and 11 matching healthy controls, we measured R‐R interval (electrocardiography), blood pressure (Portapres®) and breathing frequency (ultrasonic device) in supine rest, during 1...
Source: Clinical Physiology and Functional Imaging - Category: Radiology Authors: Tags: Original Article Source Type: research
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