A possible role of FANCM mutations in male breast cancer susceptibility: Results from a multicenter study in Italy.

CONCLUSION: Rare FANCM truncating mutations, other than c.5101C>T and c.5791C>T, may have a role in MBC susceptibility. The inclusion of FANCM in gene panels for research purpose would allow for the identification of a higher number of mutation carriers, thus helping estimate BC risk associated with FANCM mutations. PMID: 29287190 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/29287190?dopt=Abstract

Source: Breast - December 26, 2017 Category: Cancer & Oncology Authors: Silvestri V, Rizzolo P, Zelli V, Valentini V, Zanna I, Bianchi S, Tibiletti MG, Varesco L, Russo A, Tommasi S, Coppa A, Capalbo C, Calistri D, Viel A, Cortesi L, Manoukian S, Bonanni B, Montagna M, Palli D, Radice P, Peterlongo P, Ottini L Tags: Breast Source Type: research