Patients with atopic dermatitis and history of eczema herpeticum elicit herpes simplex virus –specific type 2 immune responses
Atopic dermatitis (AD) is an inflammatory, relapsing skin disorder that affects 15% to 25% of children worldwide and persists in adulthood in around 25% of these cases.1 About 3% to 8% of patients with AD seem to have a disturbance in viral clearance, manifesting severe forms of molluscum contagiosum, papilloma virus, and most prominently, the generalized cutaneous infection with herpes simplex virus 1 (HSV1), called eczema herpeticum (EH),2,E1,E2 which can lead to life-threatening complications.
Source: Journal of Allergy and Clinical Immunology - Category: Allergy & Immunology Authors: Stephan Traidl, Petra Kienlin, Gabriele Begemann, Lichen Jing, David M. Koelle, Thomas Werfel, Lennart M. Roesner Tags: Letter to the Editor Source Type: research
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