Synthetic protein packages its own genetic material and evolves

(University of Washington Health Sciences/UW Medicine) Scientists have created computationally designed protein assemblies, that display some functions normally associated with living things, in the search for ways to transport therapeutic cargo into specific types of cells without using viruses as vehicles. These encapsulate their own RNA genomes and evolve new traits in complex environments. They are synthetic versions of the protein shells that viruses use to protect and deliver materials. The synthetic proteins evolved better RNA packaging, resistance against degrading enzymes in blood and longer circulation time.
Source: EurekAlert! - Biology - Category: Biology Source Type: news