Practice Advisory for the Prevention of Perioperative Peripheral Neuropathies 2018 An Updated Report by the American Society of Anesthesiologists Task Force on Prevention of Perioperative Peripheral Neuropathies *

Update Highlights This Practice Advisory updates the “Practice Advisory for the Prevention of Perioperative Peripheral Neuropathies: An Updated Report by the American Society of Anesthesiologists Task Force on the Prevention of Perioperative Peripheral Neuropathies,” adopted by the American Society of Anesthesiologists in 2010 and published in 201 1.†† In October 2016, the Committee on Standards and Practice Parameters elected to search for new evidence to determine if recommendations in the existing Practice Advisory continue to be supported by current evidence. The resultant Advisory, presented in this issue, includes an update of the s cientific literature and an updated format for individual recommendations. Seven hundred and ninety-five new citations covering the period of January 1, 1999, through July 31, 2009, were identified and reviewed, with 31 new studies meeting the inclusion/exclusion criteria established by the Task For ce. These studies were combined with studies reviewed and accepted by the previous update, resulting in a total of 114 articles found acceptable as evidence. The new literature consisted entirely of observational findings or case reports that found neuropathies occurring in brachial plexus, ulnar, r adial, sciatic, femoral, and peroneal (fibular) nerves. The evidence continues to support the existing recommendations that address positioning strategies, protective padding, and proper placement of equipment as useful preve...
Source: Anesthesiology - Category: Anesthesiology Source Type: research

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COBALT IS an essential trace element involved in vitamin B12 and myocardial metabolism. Although biologically necessary for normal physiologic function, cobalt can cause serious adverse health effects at high exposure levels.1 Several case reports of patients with metal-on-metal implants or occupational exposure have suggested that elevated serum cobalt levels may lead to a variety of different systemic symptoms or complications including neurologic (auditory and visual impairment, cognitive decline, peripheral neuropathy); cardiovascular (cardiomyopathy and arrhythmias); and endocrine (hypothyroidism) abnormalities.
Source: Journal of Cardiothoracic and Vascular Anesthesia - Category: Anesthesiology Authors: Tags: Case Report Source Type: research
Conclusions: A high incidence (19%) of intraoperative nerve insult was observed in this study demonstrating the feasibility of using an automated SSEP device to provide a timely alert and enable an intervention in order to minimize peripheral nerve injury during TSA. Further randomized studies are warranted.
Source: Journal of Neurosurgical Anesthesiology - Category: Anesthesiology Tags: Clinical Investigations Source Type: research
​BY JENNIFER TUONG; IVAN KHARCHENKO; JEAN LUC AGARD; &AHMED RAZIUDDIN, MDA 65-year-old man who had HIV well-controlled with highly active antiretroviral therapy, hypertension, sciatica, and restless leg syndrome presented to the emergency department with left leg pain. He also had had chemotherapy and radiation for anal cancer. The patient said the pain had started 45 minutes earlier when he was sitting on the toilet.He described the pain as sore in quality and 10/10 on the pain scale. He reported that it had started in his lower back and radiated to his left leg. He said he had had no trauma or weakness to the regio...
Source: The Case Files - Category: Emergency Medicine Tags: Blog Posts Source Type: research
In the past 10 years, the safety of fluoroquinolone antibiotics has been under scrutiny in medical literature. To date, the United States Food and Drug Administration (FDA) has issued a number of warnings about the risks of fluoroquinolones and their potential to cause a number of complications, including peripheral neuropathy, tendinitis, and tendon rupture. In December, 2018, the FDA issued a new alert suggesting that fluoroquinolones can increase the occurrence of aortic aneurysms and aortic dissections.
Source: Journal of Cardiothoracic and Vascular Anesthesia - Category: Anesthesiology Authors: Tags: Editorial Source Type: research
In this study, we explored the effect of vitamin B12 on nerve regeneration after TBI both in vivo and in vitro. Meanwhile, we investigated the role of ER stress during the vitamin B12 treatment for TBI by inspecting changes in neuronal apoptosis, microtubule, myelin regeneration, and axonal growth. Materials and Methods Animals Adult C57BL/6 male mice aged 6–8 weeks and weighing 20–26 g were purchased from the Animal Center of the Chinese Academy of Sciences (Shanghai, China). Animals were housed under a 12-h light/dark cycle at 21–23°C and provided access to food and water ad libitum. The care and...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Anna M. D. Watson1,2*, Eleanor A. M. Gould2, Sally A. Penfold2, Gavin W. Lambert2,3, Putra Riza Pratama2, Aozhi Dai1, Stephen P. Gray2, Geoffrey A. Head2† and Karin A. Jandeleit-Dahm1,2† 1Department of Diabetes, Central Clinical School, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, VIC, Australia 2Baker Heart and Diabetes Institute, Melbourne, VIC, Australia 3Iverson Health Innovation Research Institute, Faculty of Health, Arts and Design, Swinburne University of Technology, Hawthorn, VIC, Australia Patients with diabetic hypertensive nephropathy have accelerated ...
Source: Frontiers in Physiology - Category: Physiology Source Type: research
This study not only provides biological evidence to support the use of duloxetine as the first standard CIPN drug but will also lead to potential new targets for CIPN drug development. Introduction A major dose-limiting complication of chemotherapy is chemotherapy-induced peripheral neuropathy (CIPN). The greatest contributors to CIPN are taxanes (e.g., paclitaxel) and platinum-based (e.g., oxaliplatin) treatments (Krukowski et al., 2015). Paclitaxel (PTX) can effectively treat several of the most common cancers including breast cancer, lung cancer, and ovarian cancer (Ewertz et al., 2015; Cetinkaya-Fisgin et al., ...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
CORONARY ARTERY BYPASS GRAFTING (CABG) surgery has been associated with different neurologic complications such as intracerebral hemorrhage, seizures, delirium, cognitive impairment, and peripheral neuropathy.1,2 Specifically, the incidence of seizures after cardiac surgery varies between 0.5% and 7.6%.3 Seizures are due mainly to thromboembolic ischemic stroke, cerebral air embolism, or specific drugs.4 When seizures occur, recurrence rates range between 40% and 66%, and an association with an abnormal outcome has been reported.
Source: Journal of Cardiothoracic and Vascular Anesthesia - Category: Anesthesiology Authors: Tags: Case Report Source Type: research
In conclusion, opioid initiation and transition to chronic opioid therapy are frequent in a peripheral neuropathy population despite few patients receiving more than one guideline-recommended medication. Efforts to decrease opioid utilization and increase guideline-recommended medication use are needed to improve current neuropathic pain treatment.
Source: Pain - Category: Anesthesiology Tags: Research Paper Source Type: research
CONCLUSION Bilateral suprazygomatic maxillary nerve block is an effective and safe alternative to the traditional peripheral nerve blocks for cleft lip and cleft palate surgery, in a mixed paediatric and adult population.
Source: European Journal of Anaesthesiology - Category: Anesthesiology Tags: Loco-regional anaesthesia Source Type: research
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