New Data To Be Presented At ASH 2017 Underscore Amgen's Commitment To Improving Lives And Changing Outcomes For Patients With Difficult-To-Treat Blood Cancers

Positive Overall Survival Data From Phase 3 ASPIRE Trial on KYPROLIS® (Carfilzomib) in Relapsed Multiple Myeloma to be Highlighted in Oral Presentation Results From Several Abstracts Highlight the Potential of Amgen's Bispecific T Cell Engager (BiTE®) Platform as an Innovative Approach to Treating Blood Cancers FDA Grants Priority Review for BLINCYTO (Blinatumomab) Supplemental Biologics License Application in Minimal Residual Disease-Positive Acute Lymphoblastic Leukemia THOUSAND OAKS, Calif., Dec. 7, 2017 /PRNewswire/ -- Amgen (NASDAQ:AMGN) today announced that new clinical data and analyses from 33 abstracts, including six oral presentations, evaluating approved medicines and inv...
Source: Amgen News Release - Category: Pharmaceuticals Tags: Uncategorized Source Type: news

Related Links:

Publication date: Available online 17 November 2018Source: The Annals of Thoracic SurgeryAuthor(s): Masaya Tamura, Isao Matsumoto, Yusuke Tanaka, Daisuke Saito, Shuhei Yoshida, Seiichi Kakegawa, Tomoyasu Kumano, Yosuke Shimizu, Hiroyasu Tamamura, Tsuyoshi Takanaka, Hirofumi TakemuraAbstractBackgroundThe aim of this study was to compare outcomes of primary treatment with stereotactic body radiation therapy (SBRT) versus sublobar resection (SLR) for clinical stage I non-small cell lung cancer (NSCLC) in patients with medical comorbidities.MethodsConsecutive patients who underwent SBRT (n=106) or SLR (wedge resection: n=100 a...
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
ConclusionsHPV prevalence in the oral mucosa of the assessed FA patients was higher than reported in the general population. Additional studies with collection of sequential samples are needed to know the natural history of the presence of multiple HPV types in these individuals and its association with the development of tumors, to evaluate the implementation of preventive measures, such as vaccination, and to guide early treatment.This article is protected by copyright. All rights reserved.
Source: Transplant Infectious Disease - Category: Transplant Surgery Authors: Tags: Original Report Source Type: research
ConclusionsWe report a case of a 67-year-old man with hypothalamic hypopituitarism secondary to a suprasellar metastasis from a primary small cell lung cancer, and we review ten cases of hypothalamic hypopituitarism due to metastases, including our patient. Recognizing hypopituitarism can be challenging, especially in the elderly, whose symptoms such as lethargy and visual decline may be mistaken for the natural aging process. In patients with established metastatic conditions, the symptoms may be wrongly attributed to malignancy or to the side effects of therapy. When a patient is suspected of having hypopituitarism, a ho...
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research
Publication date: Available online 16 November 2018Source: Mutation Research/Genetic Toxicology and Environmental MutagenesisAuthor(s): Donatella Feretti, Roberta Pedrazzani, Elisabetta Ceretti, Mario Dal Grande, Ilaria Zerbini, Gaia Claudia Viviana Viola, Umberto Gelatti, Francesco Donato, Claudia ZaniAbstractAir pollution has well-known harmful effects on human beings, causing both acute and chronic diseases. Some data suggest that genetic damage occurring early in life may influence the risk of having cancer and other chronic diseases in adulthood. Therefore, there is a growing interest in studying the genotoxic activit...
Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis - Category: Genetics & Stem Cells Source Type: research
ConclusionRadium-223 is a valuable therapeutic alternative in the treatment of patients with mCRPC in early stages of the disease, with a good safety profile. Its benefits extend to the bone environment.ResumenContextoEliminar las metástasis óseas, restaurar/preservar la morfología ósea y prevenir/retrasar los eventos óseos constituyen un objetivo fundamental en el manejo del cáncer de próstata resistente a la castración metastásico (CPRCm). Radio-223 es la primera terapia alfa-dirigida con acción sobre el hueso que aumenta la supervivencia en estos paci...
Source: Actas Urologicas Espanolas - Category: Urology & Nephrology Source Type: research
Publication date: December 2018Source: American Journal of Preventive Medicine, Volume 55, Issue 6Author(s):
Source: American Journal of Preventive Medicine - Category: International Medicine & Public Health Source Type: research
Publication date: December 2018Source: American Journal of Preventive Medicine, Volume 55, Issue 6Author(s):
Source: American Journal of Preventive Medicine - Category: International Medicine & Public Health Source Type: research
This study aimed to review the effect of decision aids on men's screening intention, screening utilization, and the congruence between intentions and uptake.Evidence acquisitionData sources were searched through April 6, 2018, and included MEDLINE, Scopus, CENTRAL, CT.gov, Cochrane report, PsycARTICLES, PsycINFO, and reference lists. This study included RCTs and observational studies of decision aids that measured prostate screening intention or behavior. The analysis was completed in April 2018.Evidence synthesisEighteen studies (13 RCTs, four before–after studies, and one non-RCT) reported data on screening intenti...
Source: American Journal of Preventive Medicine - Category: International Medicine & Public Health Source Type: research
Publication date: Available online 16 November 2018Source: The Lancet Respiratory MedicineAuthor(s): Michael A Matthay, Carolyn S Calfee, Hanjing Zhuo, B Taylor Thompson, Jennifer G Wilson, Joseph E Levitt, Angela J Rogers, Jeffrey E Gotts, Jeanine P Wiener-Kronish, Ednan K Bajwa, Michael P Donahoe, Bryan J McVerry, Luis A Ortiz, Matthew Exline, John W Christman, Jason Abbott, Kevin L Delucchi, Lizette Caballero, Melanie McMillan, David H McKennaSummaryBackgroundTreatment with bone-marrow-derived mesenchymal stromal cells (MSCs) has shown benefits in preclinical models of acute respiratory distress syndrome (ARDS). Safety ...
Source: The Lancet Respiratory Medicine - Category: Respiratory Medicine Source Type: research
More News: Acute Leukemia | Acute Lymphoblastic Leukemia | Cancer | Cancer & Oncology | Grants | Leukemia | Myeloma | Oral Cancer | Pharmaceuticals