MKSAP: 25-year-old man positive for hepatitis B surface antigen
Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians.
A 25-year-old man is evaluated in follow-up after recently testing positive for hepatitis B surface antigen. He underwent testing as part of the immigration process from Somalia. Two other siblings also have hepatitis B virus (HBV) infection.
On physical examination, he is a young, healthy-appearing man. Vital signs are normal. No jaundice is noted, and the abdominal examination is unremarkable.
Laboratory studies:
Alanine aminotransferase
Normal
Aspartate aminotransferase
Normal
α-Fetoprotein
Normal
Hepatitis B surface antigen
Positive
Hepatitis B e antibody
Positive
Hepatitis B e antigen
Negative
HBV DNA
896 IU/mL
Ultrasound of the upper abdomen is normal.
Which of the following is the most appropriate management?
A. Administration of hepatitis B vaccine
B. Administration of pegylated interferon
C. Administration of tenofovir
D. α-Fetoprotein measurement every 12 months
E. Ultrasound imaging of the liver every 6 months
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Source: Kevin, M.D. - Medical Weblog - Category: General Medicine Authors: < a href="https://www.kevinmd.com/blog/post-author/mksap" rel="tag" > mksap < /a > Tags: Conditions Gastroenterology Oncology/Hematology Source Type: blogs
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