Block matching sparsity regularization-based image reconstruction for incomplete projection data in computed tomography.
Block matching sparsity regularization-based image reconstruction for incomplete projection data in computed tomography. Phys Med Biol. 2017 Nov 30;: Authors: Cai A, Li L, Zheng Z, Zhang H, Wang L, Hu G, Yan B Abstract In medical imaging fields, many of the conventional regularization meth-ods, such as total variation or total generalized variation, impose strong prior assumptions on images which can only account for very limited classes of im-ages. A more reasonable sparse representation frame for images is still in strong need. Visually understandable images contain meaningful patterns and the combinations or collections of these patterns can be utilized to form some sparse and redundant representations which can promisingly facilitate image reconstructions. In this work, we propose and study the block matching spar-sity regularization (BMSR) and devise the optimization program using BMSR for computed tomography (CT) image reconstruction for incomplete projec-tion set. The program is built as a constrained optimization, minimizing the L1-norm of the coefficients of the image in the transformed domain subject to the data observation and positivity of image itself. To solve the program effi-ciently, a practical algorithm based on the proximal point algorithm is devel-oped and analyzed. In order to accelerate the convergence rate, a practical strategy for tuning the BMSR parameter is proposed and applied. The experi-mental results of various settings, inc...
In conclusion, a novel yet reliable method for the measurement of intracellular 18F-FDG via GS has been developed, and our results indicate that 18F-FDG uptake is associated with radiation and cetuximab response in HNSCC. PMID: 31620196 [PubMed]
We present unusual treatment outcome in a 59-year-old male diagnosed with metastatic lung adenocarcinoma with a very good response to ruxolitinib as monotherapy. In June 2017, this patient was diagnosed with myeloproliferative neoplasm – Janus-associated kinases 2 positive – and in December 2017 ruxolitinib therapy was started. At the same time, patient was diagnosed with lung adenocarcinoma in the left lower lobe with positive anaplastic lymphoma kinase mutation and with right lower lobe metastasis. Because of partial regression of tumor size noted on the computed tomography (CT) scans during tumor investigati...
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