Abnormal dendritic calcium activity and synaptic depotentiation occur early in a mouse model of Alzheimer ’s disease

Alzheimer ’s disease (AD) is characterized by amyloid deposition, tangle formation as well as synapse loss. Synaptic abnormalities occur early in the pathogenesis of AD. Identifying early synaptic abnormalities...

Source: Molecular Neurodegeneration - November 14, 2017 Category: Neurology Authors: Yang Bai, Miao Li, Yanmei Zhou, Lei Ma, Qian Qiao, Wanling Hu, Wei Li, Zachary Patrick Wills and Wen-Biao Gan Tags: Research article Source Type: research