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The importance of audiometric monitoring in patients with multidrug-resistant tuberculosis

CONCLUSIONS: Evaluations of ototoxicity symptoms were not usually reported in the routine care of patients with MDR-TB. Complaints of tinnitus were associated with amikacin and streptomycin use. These results require confirmation in future studies.
Source: Revista da Sociedade Brasileira de Medicina Tropical - Category: Tropical Medicine Source Type: research

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Seventeen cases of tuberculosis were recorded in Allegheny County last year.
Source: bizjournals.com Health Care:Pharmaceuticals headlines - Category: Pharmaceuticals Authors: Source Type: news
UPMC said Friday a UPMC Presbyterian ER employee developed tuberculosis and the system is notifying and testing patients and staff who may have come in contact with the employee. The employee of the Presby emergency department, who was not identified, is on medical leave and recovering at home. UPMC said the employee had also been a patient at a doctor’s office at Magee-Womens Hospital of UPMC and the ophthalmology clinic at Presby. Tuberculosis is an airborne disease c aused by bacteria that…
Source: bizjournals.com Health Care:Physician Practices headlines - Category: American Health Authors: Source Type: news
Conclusion: We demonstrate that hearing threshold levels can be estimated from ear-EEG recordings made from electrodes placed in one ear. Significance: Objective hearing threshold estimation based on ear-EEG can be integrated into hearing aids, thereby allowing hearing assessment to be performed by the hearing instrument on a regular basis.
Source: IEEE Transactions on Biomedical Engineering - Category: Biomedical Engineering Source Type: research
AbstractTo determine, among systemic lupus erythematosus patients, factors associated with active tuberculosis. We performed a case-control study, in a tertiary-care center in Mexico City. We defined cases as systemic lupus erythematosus patients with active tuberculosis and matched them 1:1 with systemic lupus erythematosus patients without tuberculosis (controls) by age, date of systemic lupus erythematosus diagnosis, and disease duration. We analyzed clinical variables, lupus disease activity (SLEDAI-2K), and accumulated damage (SLICC/ARC-DI). We performed a nonconditional logistic regression to determine factors associ...
Source: Clinical Rheumatology - Category: Rheumatology Source Type: research
Publication date: June 2018 Source:Journal of Global Antimicrobial Resistance, Volume 13 Author(s): Hong Lu, Xiaoxiao Zhang, Yizhi Zhang, Haiyang Liu, Chunquan Xu, Majun Zhang, Wenzi Bi, Tieli Zhou
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
Publication date: Available online 19 April 2018 Source:The Brazilian Journal of Infectious Diseases Author(s): Suzana Batista Vereza de Oliveira, Ângelo Ferreira Passos, David Jamil Hadad, Lorena Zbyszynski, Pedro Sousa de Almeida Júnior, Luiz Guilherme Schmidt Castellani, Reynaldo Dietze, Moisés Palaci Tuberculosis (TB) is an infectious disease of global importance with major economic and social burden accounting for 25% of all avoidable deaths in developing countries. Extrapulmonary involvement may occur either in association with clinically apparent pulmonary tuberculosis or in isolation. This cros...
Source: The Brazilian Journal of Infectious Diseases - Category: Infectious Diseases Source Type: research
Vaibhav Kumar Jain, Vivek Singh, Vikas Kannaujia, Priyadarshini Mishra, Rajendra Vishnu Phadke, Kumudini SharmaIndian Journal of Ophthalmology 2018 66(5):714-717 This case series aimed to review the significance of revisiting papilledema after successful cerebral venous sinus thrombosis (CVST) management with sinus angioplasty. Four patients presented with blurring and transient obscuration of vision with papilledema, headache, tinnitus, and vomiting. On magnetic resonance venography and digital subtraction angiography, chronic transverse sinus thrombosis was diagnosed for which patients underwent endovascular interventio...
Source: Indian Journal of Ophthalmology - Category: Opthalmology Authors: Source Type: research
AbstractThe role of metformin (MET) on treatment effect of diabetic tuberculosis (TB) patients has not been studied in China. Thus, we conducted a retrospective study to investigate whether MET exhibited more efficacy in combination with anti-TB regimens for diabetic TB patients. All patients recruited came from five tuberculosis control and prevention institutes from July 2009 to July 2016 and completed 3  years of follow-up. We used chi-square test or Fisher’s exact test to evaluate the demographic characteristics and the frequency of clinical outcome between MET and non-MET group. A total of 58 TB patients wi...
Source: European Journal of Clinical Microbiology and Infectious Diseases - Category: Microbiology Source Type: research
AbstractTuberculosis (TB) remains one of the most deadly infections with approximately a quarter of cases not being identified and/or treated mainly due to a lack of resources. Rapid detection of TB or drug-resistant TB enables timely adequate treatment and is a cornerstone of effective TB management. We evaluated the analytical performance of a single-tube assay for multidrug-resistant TB (MDR-TB) on an experimental platform utilising RT-PCR and melting curve analysis that could potentially be operated as a point-of-care (PoC) test in resource-constrained settings with a high burden of TB. Firstly, we developed and evalua...
Source: European Journal of Clinical Microbiology and Infectious Diseases - Category: Microbiology Source Type: research
AbstractPurpose of the reviewEnterococci are emerging threatening multidrug-resistant bacteria.Enterococcus faecium is a common pathogen associated with severe hospital-acquired infections. The goal of this report is to analyze the evolution of this nosocomial pathogen and study the state of adequate infection control measures.Recent findingsEvolution over millions of years has allowed enterococci to develop into a persistent hospital pathogen, an environment where it thrives. Vancomycin-resistant enterococci (VRE) continues to obtain antibiotic resistance elements. Enterococci assemble multiple virulence factors. VRE inte...
Source: Current Treatment Options in Infectious Diseases - Category: Infectious Diseases Source Type: research
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