End-of-Life and Palliative Needs of Adolescents and Young Adults (AYA) with Serious Illnesses (R01 Clinical Trial Optional)

Funding Opportunity PA-18-137 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement (FOA) is to foster research on the unique perspectives, needs, wishes, and decision-making processes of adolescents and young adults (AYA; defined by the World Health Organization and the Centers for Disease Control and Prevention as youth between 12 24 years of age) with serious, advanced illnesses; and research focused on specific end-of-life/palliative care (EOLPC) models that support the physical, psychological, spiritual, and social needs of AYA with serious illness, their families and caregivers.
Source: NIH Funding Opportunities (Notices, PA, RFA) - Category: Research Source Type: funding

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Authors: Schweighardt AE, Juba KM Abstract Acetaminophen is among the most commonly used nonopioid analgesics, but significant variation exists in its prescribing practices for cirrhosis patients. Our primary objective was to describe the quality of evidence supporting or refuting the use of acetaminophen in patients with hepatic dysfunction. A comprehensive literature review of PubMed, Cochrane Library, Web of Science, and International Pharmaceutical Abstracts using the search terms "acetaminophen," "paracetamol," "chronic liver disease," "cirrhosis," and "hepatic dise...
Source: Journal of Pain and Palliative Care Pharmacotherapy - Category: Palliative Care Tags: J Pain Palliat Care Pharmacother Source Type: research
Authors: Wales J, Kalia S, Moineddin R, Husain A Abstract BACKGROUND: Socioeconomic disparities in home death have been noted in the literature. Home-based palliative care increases access to home death and has been suggested as a means to decrease these disparities. AIM: Our study examines the association between socioeconomic status and other demographic factors on place of death in a population receiving home palliative care in Toronto, Canada. DESIGN: This is a retrospective chart review of patients who died between August 2013 and August 2015 when admitted to a home-based palliative care service. Multi...
Source: Journal of Palliative Care - Category: Palliative Care Tags: J Palliat Care Source Type: research
Patient safety and quality of care are increasing concerns for healthcare internationally. This paper examines the spatial achievement of safety and wellbeing by healthcare staff, patients and their carers within UK primary care and Australian palliative c...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Jurisprudence, Laws, Legislation, Policies, Rules Source Type: news
Publication date: Available online 18 June 2019Source: Respiratory Medicine Case ReportsAuthor(s): Daisuke Shibahara, Makoto Furugen, Shiho Kasashima, Kozue Kaneku, Tomoko Yamashiro, Wakako Arakaki, Takuro Ariga, Eriko Atsumi, Hajime Aoyama, Hirofumi Matsumoto, Hiroki Maehara, Jiro FujitaAbstractA 70-year-old Japanese man with stage IV EGFR-mutated lung adenocarcinoma complained of right mild back pain. The patient had been heavily treated with several cytotoxic or molecular targeted agents for 10 years and received a palliative radiation therapy of 2nd sacral vertebra 5 years ago. Computed tomography showed the abnormal l...
Source: Respiratory Medicine Case Reports - Category: Respiratory Medicine Source Type: research
Conclusion Considering the domains of HRQoL of the women treated for cervical cancer, a better score was observed in the domains of physical and social/family wellbeing. For most domains, better scores were found between those with a current occupation, with a longer time after the diagnosis and treatment, and among those who had undergone a hysterectomy.Resumo Objetivo Analisar os fatores associados à qualidade de vida em mulheres com câncer de colo do útero tratadas em um hospital de referência no Rio de Janeiro, RJ, Brasil. Métodos Estudo transversal em mulheres com diagnóstico de...
Source: Revista Brasileira de Ginecologia e Obstetricia - Category: OBGYN Source Type: research
Conclusions: Methods for delivering compassionate care at EOL are wide ranging, but barriers on a systemic and individual level should be addressed to make its practice more widespread. This can be accomplished, in part, by the standardization of EOL conversations, training physicians how to have meaningful EOL conversations, and integration of such conversations into electronic medical records. PMID: 31204909 [PubMed - in process]
Source: International Journal of Qualitative Studies on Health and Well-being - Category: International Medicine & Public Health Tags: Int J Qual Stud Health Well-being Source Type: research
Endoscopic colonic stent placement is recommended by international guidelines as the preferred treatment for the palliation of obstructing left-sided colonic cancer.1,2 The main arguments in favor of stent placement in comparison with emergency surgery for the palliation of malignant left-sided colonic obstructing lesions are the significantly lower stoma rates, shorter period of hospitalization, and earlier initiation of palliative systemic therapy. The largest meta-analysis on this topic included a total of 837 patients from 10 observational and 3 randomized studies comparing stent placement and surgery for incurable mal...
Source: Gastrointestinal Endoscopy - Category: Gastroenterology Authors: Tags: Original article Source Type: research
Publication date: Available online 17 June 2019Source: European Journal of Surgical OncologyAuthor(s): Robin Detering, Eleonora G. Karthaus, Wernard A.A. Borstlap, Corrie A.M. Marijnen, Cornelis J.H. van de Velde, Willem A. Bemelman, Geerard L. Beets, Pieter J. Tanis, Arend G.J. Aalbers, A.G.J. Aalbers, Y. Acherman, G.D. Algie, B. Alting von Geusau, F. Amelung, T.S. Aukema, I.S. Bakker, S.A. Bartels, S. Basha, A.J.N.M. Bastiaansen, E. BelgersAbstractIntroductionOptimized treatment of primary rectal cancer might have influenced treatment characteristics and outcome of locally recurrent rectal cancer (LRRC). Subgroup analysi...
Source: European Journal of Surgical Oncology (EJSO) - Category: Surgery Source Type: research
This study has terrific significance and could be extremely important,” Harbut, clinical professor of internal medicine at Wayne State University and Michigan State University, told The Mesothelioma Center at Asbestos.com. “We’re going after this one with great guns.” The study is part of a new partnership between Owlstone Medical — the Breath Biopsy inventor in the United Kingdom — and the International Association of Heat and Frost Insulators and Allied Workers, a building trade union that covers the United States and Canada. Early Diagnosis Still a Rarity The first part of the study ...
Source: Asbestos and Mesothelioma News - Category: Environmental Health Authors: Source Type: news
Source: Therapeutics and Clinical Risk Management - Category: Drugs & Pharmacology Tags: HIV/AIDS - Research and Palliative Care Source Type: research
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