The relationship between esophageal acid exposure and the esophageal response to volumetric distention

ConclusionsAbnormal esophageal acid exposure was associated with an impaired contractile response to volume distention of the esophagus. This supports that acid exposure is dependent on acid clearance mechanisms.

Among patients evaluated for reflux with wireless esophageal pH testing and the functional lumen imaging probe, a response to volumetric distension comprising repetitive, antegrade contractions (as in A) was associated with a reduced degree of esophageal acid exposure. The esophagogastric‐junction distensibility index, however, was poorly correlated with esophageal acid exposure.

Source: Neurogastroenterology and Motility - November 1, 2017 Category: Gastroenterology Authors: D. A. Carlson, P. Kathpalia, J. Craft, M. Tye, Z. Lin, P. J. Kahrilas, J. E. Pandolfino Tags: ORIGINAL ARTICLE Source Type: research