Circulating matrix metalloproteinases are associated with arterial stiffness in patients with type 1 diabetes: pooled analysis of three cohort studies

Altered regulation of extracellular matrix (ECM) composition by matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinase (TIMPs) may contribute to arterial stiffening. We investigated associ...
Source: Cardiovascular Diabetology - Category: Cardiology Authors: Tags: Original investigation Source Type: research

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We evaluated fall frequency and factors affecting falls among middle-aged and older adults with type 1 diabetes (T1D) from T1D Exchange Registry. Twenty-nine percent of T1D participants reported falls within the past 12  months. Severe hypoglycemia, diabet...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news
Source: BMJ Comments - Category: General Medicine Source Type: forums
DIABETES is a condition where the body can no longer control blood sugar levels. There are two main types: Diabetes type 1 which usually appears at birth and Diabetes type 2 which can appear in later life. If you ’re a sufferer, eating these berries could help you maintain your blood sugar levels.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
DIABETES is a condition where the body struggles to control blood sugar levels. There are several different forms including diabetes type 1, which appears after birth, and diabetes type 2, which may develop later in life. Adding this powder to your diet could help control your blood sugar levels.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
DIABETES is a condition where the body struggles to control blood sugar levels. There are several different forms including diabetes type 1, which appears after birth, and diabetes type 2, which may develop later in life. Adding this powder to your diet could help control your blood sugar levels.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Condition:   Diabetes Mellitus, Type 1 Interventions:   Device: CGM+CSII;   Device: MDI with degludec Sponsor:   Azienda Ospedaliero-Universitaria Careggi Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Authors: Farooq T, Rehman K, Hameed A, Akash MSH Abstract Type 1 diabetes mellitus (T1DM) is classified as an autoimmune disease which progressively results in the depletion of insulin-secreting β-cells. Consequently, the insulin secretion stops leading to hyperglycemic situations within the body. Under severe conditions, it also causes multi-organ diabetes-associated dysfunctionalities notably hypercoagulability, neuropathy, nephropathy, retinopathy, and sometimes organ failures. The prevalence of this disease has been noticed about 3% that has highlighted the serious concerns for healthcare professionals aro...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
Condition:   Diabetes Mellitus, Type 1 Interventions:   Device: CGM+CSII;   Device: MDI with degludec Sponsor:   Azienda Ospedaliero-Universitaria Careggi Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Publication date: 15 October 2018 Source:Biosensors and Bioelectronics, Volume 117 Author(s): R. Perrier, A. Pirog, M. Jaffredo, J. Gaitan, B. Catargi, S. Renaud, M. Raoux, J. Lang On-line and real-time analysis of micro-organ activity permits to use the endogenous analytical power of cellular signal transduction algorithms as biosensors. We have developed here such a sensor using only a few pancreatic endocrine islets and the avoidance of transgenes or chemical probes reduces bias and procures general usage. Nutrient and hormone-induced changes in islet ion fluxes through channels provide the first integrative read-out o...
Source: Biosensors and Bioelectronics - Category: Biotechnology Source Type: research
Publication date: 16–22 June 2018 Source:The Lancet, Volume 391, Issue 10138 Author(s): Linda A DiMeglio, Carmella Evans-Molina, Richard A Oram Type 1 diabetes is a chronic autoimmune disease characterised by insulin deficiency and resultant hyperglycaemia. Knowledge of type 1 diabetes has rapidly increased over the past 25 years, resulting in a broad understanding about many aspects of the disease, including its genetics, epidemiology, immune and β-cell phenotypes, and disease burden. Interventions to preserve β cells have been tested, and several methods to improve clinical disease management have been a...
Source: The Lancet - Category: General Medicine Source Type: research
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