Sometimes the Eyes Say More Than the Mouth
A 48-year-old man with a history of human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS)-associated cryptococcal meningitis was referred to our hospital with blurred vision in his left eye for several months. He was diagnosed with bilateral chronic posterior uveitis (Figure). After ruling out secondary uveitis, such as sarcoidosis, Beh çet disease, Vogt-Koyanagi-Harada disease, herpesvirus infection, and tuberculosis, uveitis was highly suspected to be attributable to syphilis, namely ocular syphilis, considering AIDS as his underlying disease and previous unprotected sexual contact with males and females.
On this episode of ASHA Voices, we dive into the research behind hearing loss reversal. While investigating a genetic form of hearing loss affecting transduction, researcher Jeff Holt found he could successfully reverse hearing loss in mice. How did the researcher test the rodents’ hearing? By unexpectedly playing loud music and looking for a response in the subjects, nicknamed Beethoven mice. “A deaf mouse doesn’t jump at all, no matter how loud a sound you play. But after introducing our gene therapy into the ears of Beethoven mice, we find they jump again,” says Holt. Also on the show, sens...
Nationwide improvements in insurance coverage and access to care seen, even in nonexpansion states
This report describes that human immunodeficiency virus partner services for transgender women must address social and structural barriers unique to this population.
Doubling the dose of influenza vaccine for pregnant women with HIV moderately improves immunogenicity compared to a single flu shot, but response remains well below that of pregnant women without HIV, a clinical trial shows.Reuters Health Information
Conclusion: The combined picture of 'low IPT initiation and high completion' seen in our study mirrors findings from other countries. Drug stock-out was the key challenge, which obliged health-care providers to prioritize 'IPT completion' over 'IPT initiation'. There is an urgent need to improve the procurement and supply chain management of isoniazid. PMID: 31937200 [PubMed - in process]
Contributors : Siyuan Feng ; Guobao TianSeries Type : Expression profiling by high throughput sequencing ; Genome binding/occupancy profiling by high throughput sequencingOrganism : Mycolicibacterium smegmatis MC2 155To understand how GreA may affect gene expression at the transcriptional level, we performed whole-transcriptome RNA-seq analyses.To examine whether GreA binds to specific chromosomal regions, we performed chromatin immunoprecipitation followed by deep sequencing (ChIP-seq) and then sought to verify the binding mode of GreA. ChIP-seq experiments were performed by using M. smegmatis strains producing GreA prote...
[Daily Maverick] You're far more likely to be offered an HIV test at a government health facility than at your GP or workplace clinic.
[The Herald] MANICALAND Province has made strides in the fight against HIV, amid indications the prevalence rate has declined compared to the national rate, a development attributed to awareness and access to treatment.
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog aka Tropical Travel Trouble 009 The diagnosis of HIV is no longer fatal and the term AIDS is becoming less frequent. In many countries, people with HIV are living longer than those with diabetes. This post will hopefully teach the basics of a complex disease and demystify some of the potential diseases you need to consider in those who are severely immunosuppressed. While trying to be comprehensive this post can not be exhaustive (as you can imagine any patient with ...