Low FoxG1 and high Olig ‐2 labelling indices define a prognostically favorable subset in IDH‐mutant gliomas

ConclusionsWhile the combined FoxG1/Olig‐2 profile may discriminate H3F3A K27‐ and G34‐mutant tumors and define a prognostically favourable subset in IDH‐mutant gliomas, our data show that labelling indices of these transcription factors overlap with adult IDH‐mutant and wildtype tumor classes.This article is protected by copyright. All rights reserved.

Source: Neuropathology and Applied Neurobiology - October 1, 2017 Category: Neurology Authors: Sarah Sch äfer, Felix Behling, Marco Skardelly, Marilin Koch, Ines Ott, Frank Paulsen, Ghazaleh Tabatabai, Jens Schittenhelm Tags: Original Article Source Type: research