Disrupted cholinergic modulation can underlie abnormal gamma rhythms in schizophrenia and auditory hallucination

In this study, we utilized a computational model of A1 to ask if disrupted cholinergic modulation could underlie abnormal gamma rhythms in schizophrenia. Furthermore, based on our simulation results, we propose potential pathology by which A1 can directly contribute to auditory hallucination.

http://link.springer.com/10.1007/s10827-017-0666-4

Source: Journal of Computational Neuroscience - October 18, 2017 Category: Neuroscience Source Type: research