High-frequency epidural stimulation across the respiratory cycle evokes phrenic short-term potentiation after incomplete cervical spinal cord injury

This study examined HF-ES and phrenic motor output following subacute and chronic incomplete cervical spinal cord injury. Short-term potentiation of phrenic bursting following HF-ES illustrates the potential for spinal stimulation to induce respiratory neuroplasticity. Increased tonic phrenic output indicates that alternatives to the continuous stimulation paradigm used in this study will be required for respiratory muscle activation after spinal cord injury.

Source: Journal of Neurophysiology - October 17, 2017 Category: Neurology Authors: Gonzalez-Rothi, E. J., Streeter, K. A., Hanna, M. H., Stamas, A. C., Reier, P. J., Baekey, D. M., Fuller, D. D. Tags: Research Articles Source Type: research