Ischemic stroke patients not receiving life-saving treatment, study finds

(Georgia State University) Ischemic stroke patients who do not receive intravelous (IV) alteplase, a clot-dissolving medication, are significantly less likely to survive, according to researchers at Georgia State University.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news

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ConclusionsCombining Gini coefficient and GIS network analysis in accessibility can be useful in quantifying and monitoring variation by region. We propose this combination as a new method for helping the government to make evidence-based healthcare planning.
Source: Health Policy and Technology - Category: Health Management Source Type: research
Authors: Gąsiorek P, Sakowicz A, Banach M, von Haehling S, Bielecka-Dabrowa A Abstract Purpose: The study is aimed at identifying echocardiographic and circulating biomarkers as well as hemodynamic indices of embolic stroke of undetermined etiology (ESUS) in patients aged
Source: Disease Markers - Category: Laboratory Medicine Tags: Dis Markers Source Type: research
THURSDAY, Oct. 17, 2019 -- For young and middle-aged veterans, posttraumatic stress disorder (PTSD) is associated with an increased risk for early incident transient ischemic attack (TIA) and ischemic stroke, according to a study published online...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
Publication date: Available online 16 October 2019Source: Epilepsy &BehaviorAuthor(s): Giada Pauletto, Francesco Bax, Gian Luigi Gigli, Simone Lorenzut, Lorenzo Verriello, Elisa Corazza, Mariarosaria ValenteAbstractAim of the studyThe aim of the study was to evaluate the clinical characteristics of patients with previous stroke (either ischemic or hemorrhagic), who developed status epilepticus (SE) mimicking a stroke relapse.Materials and methodsWe performed a retrospective cohort study of patients brought to hospital by the emergency service between December 2016 and January 2018 with a stroke code as possible candida...
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
Publication date: Available online 15 October 2019Source: Journal of Pharmacological SciencesAuthor(s): Takahiko Imai, Sena Iwata, Daisuke Miyo, Shinsuke Nakamura, Masamitsu Shimazawa, Hideaki HaraAbstractReperfusion injury is a serious problem in ischemic stroke therapy, which leads to neuronal damage and intracranial hemorrhage (ICH). A novel free radical scavenger, NSP-116, has anti-oxidative effect and may ameliorate reperfusion injury. The purpose of this study was to investigate the effects of NSP-116 on both ischemic and hemorrhagic stroke models.First, we assessed whether NSP-116 has protective effects in vitro. Pr...
Source: Journal of Pharmacological Sciences - Category: Drugs & Pharmacology Source Type: research
AbstractThe optimal management of oral anticoagulation (OAC) in the acute phase of non valvular atrial fibrillation (NVAF)-related acute ischemic stroke (AIS) remains controversial, especially in very old patients. Therefore, the aim of our study was to evaluate the practical management of OAC in this context. We conducted an observational retrospective study on patients 85-years old and older admitted to two Italian hospitals for NVAF-related AIS. For each patient, clinical and brain computed tomography data were recorded. Type of OAC (vitamin K antagonists, VKAs or Direct Oral Anticoagulants, DOACs), dosage and starting ...
Source: Journal of Thrombosis and Thrombolysis - Category: Hematology Source Type: research
Notoginsenoside R1 (NGR1) exerts pharmacological actions for a variety of diseases such as myocardial infarction, ischemic stroke, acute renal injury, and intestinal injury. Here, we conducted a preclinical systematic review of NGR1 for ischemia reperfusion (I/R) injury. Eight databases were searched from their inception to February 23rd, 2019; Review Manager 5.3 was applied for data analysis. CAMARADES 10-item checklist and cell 10-item checklist were used to evaluate the methodological quality. Twenty-five studies with 304 animals and 124 cells were selected. Scores of the risk of bias in animal studies ranged from 3 to ...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Conditions:   Ischemic Stroke;   Acute Stroke Interventions:   Device: ZOOM Reperfusion Catheter;   Device: Trevo® Pro (Stryker) or Solitaire™ (Medtronic) Stent Retrievers Sponsor:   Imperative Care, Inc. Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Ischemic Stroke;   Acute Stroke Interventions:   Device: ZOOM Reperfusion Catheter;   Device: Trevo® Pro (Stryker) or Solitaire™ (Medtronic) Stent Retrievers Sponsor:   Imperative Care, Inc. Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Stroke incidence rates have fallen in high-income countries over the last several decades, but findings regarding the trend over recent years have been mixed. The aim of the study was to describe and model tem...
Source: BMC Health Services Research - Category: General Medicine Authors: Tags: Research article Source Type: research
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