Near-infrared spectroscopic imaging (NIRS) along with intravascular ultrasound (IVUS)

A new combination catheter system with ability for intravascular ultra sound imaging (IVUS) along with near-infrared spectroscopic imaging (NIRS) has been developed as the TVC Imaging System TM (MC 7 system, InfraReDx, Burlington, Massachusetts). NIRS is able to detect lipid rich core of the plaques and assigns red colour to low probability and yellow colour to high probability. IBIS-3 (Integrated Biomarker and Imaging Study 3) [Simsek C et al. EuroIntervention. 2012 Jun 20;8(2):235-41. The ability of high dose rosuvastatin to improve plaque composition in non-intervened coronary arteries: rationale and design of the Integrated Biomarker and Imaging Study-3 (IBIS-3)] evaluating the effect of rosuvastatin on lipid rich coronary plaques is utilizing this combo catheter. NIRS imaging is done with a motorised catheter pull back at a speed of 0.5 millimeter per second. The amount of lipid core plaque is displayed as a chemogram with pull back position in millimeters on x-axis and the circumferential position of the measurement in degrees on on the y-axis as if the coronary vessel is split open on the longitudinal axis. Red pixels indicates no lipid and yellow pixels indicates more than 60% while black indicates lack of enough data. NIRS derived lipid core burden index (LCBI) score is calculated by multiplying the fraction of valid yellow pixels by 1000.
Source: Cardiophile MD - Category: Cardiology Authors: Tags: Angiography and Interventions chemogram combo catheter intravascular ultra sound imaging intravascular ultrasound IVUS LCBI lipid core burden index Near-infrared spectroscopic imaging NIRS NIRS - IVUS combo catheter rich coronary pla Source Type: blogs